MP705_ARATH
ID MP705_ARATH Reviewed; 513 AA.
AC Q8GYX3; O23565; Q9M0M6;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=Microtubule-associated protein 70-5;
DE Short=AtMAP70-5;
DE AltName: Full=70 kDa microtubule-associated protein 5;
GN Name=MAP70.5; OrderedLocusNames=At4g17220; ORFNames=dl4645c, FCAALL.385;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=15860013; DOI=10.1111/j.1365-313x.2005.02393.x;
RA Korolev A.V., Chan J., Naldrett M.J., Doonan J.H., Lloyd C.W.;
RT "Identification of a novel family of 70 kDa microtubule-associated proteins
RT in Arabidopsis cells.";
RL Plant J. 42:547-555(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [7]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=17567681; DOI=10.1242/jcs.007393;
RA Korolev A.V., Buschmann H., Doonan J.H., Lloyd C.W.;
RT "AtMAP70-5, a divergent member of the MAP70 family of microtubule-
RT associated proteins, is required for anisotropic cell growth in
RT Arabidopsis.";
RL J. Cell Sci. 120:2241-2247(2007).
RN [8]
RP FUNCTION, SUBCELLULAR LOCATION, INDUCTION, SUBUNIT, AND INTERACTION WITH
RP MAP70.1.
RX PubMed=20399097; DOI=10.1016/j.cub.2010.02.057;
RA Pesquet E., Korolev A.V., Calder G., Lloyd C.W.;
RT "The microtubule-associated protein AtMAP70-5 regulates secondary wall
RT patterning in Arabidopsis wood cells.";
RL Curr. Biol. 20:744-749(2010).
CC -!- FUNCTION: Plant-specific protein that interact with microtubules and
CC regulates microtubule dynamics. May play a role in anisotropic cell
CC expansion and organ growth. In association with MAP70.1, is essential
CC for the normal banding pattern of secondary cell wall and for the
CC proper development of xylem tracheary elements and wood formation.
CC {ECO:0000269|PubMed:17567681, ECO:0000269|PubMed:20399097}.
CC -!- SUBUNIT: Interacts with MAP70.1 and itself.
CC {ECO:0000269|PubMed:20399097}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000269|PubMed:17567681, ECO:0000269|PubMed:20399097}.
CC Note=Associated to microtubules in tracheary elements.
CC -!- INDUCTION: Induced upon xylem tracheary elements differentiation.
CC {ECO:0000269|PubMed:20399097}.
CC -!- MISCELLANEOUS: Plant silencing MAP70.5 show reduced inflorescence stem
CC length and diameter, and inhibition of cell expansion. Over-expression
CC of MAP70.5 causes epidermal cells to swell, stunted growth and induces
CC right-handed organ twisting.
CC -!- SIMILARITY: Belongs to the MAP70 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB10503.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78725.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AM086442; CAJ31082.1; -; mRNA.
DR EMBL; Z97343; CAB10503.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161546; CAB78725.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83864.1; -; Genomic_DNA.
DR EMBL; BT005901; AAO64836.1; -; mRNA.
DR EMBL; AK117336; BAC42006.1; -; mRNA.
DR PIR; B71441; B71441.
DR RefSeq; NP_193455.2; NM_117827.3.
DR AlphaFoldDB; Q8GYX3; -.
DR SMR; Q8GYX3; -.
DR BioGRID; 12727; 27.
DR IntAct; Q8GYX3; 28.
DR STRING; 3702.AT4G17220.1; -.
DR PaxDb; Q8GYX3; -.
DR PRIDE; Q8GYX3; -.
DR ProteomicsDB; 238267; -.
DR EnsemblPlants; AT4G17220.1; AT4G17220.1; AT4G17220.
DR GeneID; 827434; -.
DR Gramene; AT4G17220.1; AT4G17220.1; AT4G17220.
DR KEGG; ath:AT4G17220; -.
DR Araport; AT4G17220; -.
DR TAIR; locus:2130734; AT4G17220.
DR eggNOG; ENOG502QS8R; Eukaryota.
DR HOGENOM; CLU_023069_0_0_1; -.
DR InParanoid; Q8GYX3; -.
DR OMA; NAIRDYK; -.
DR OrthoDB; 745872at2759; -.
DR PhylomeDB; Q8GYX3; -.
DR PRO; PR:Q8GYX3; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8GYX3; baseline and differential.
DR Genevisible; Q8GYX3; AT.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; ISS:TAIR.
DR GO; GO:0008017; F:microtubule binding; ISS:TAIR.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0007010; P:cytoskeleton organization; TAS:TAIR.
DR GO; GO:0009832; P:plant-type cell wall biogenesis; IMP:TAIR.
DR GO; GO:0010051; P:xylem and phloem pattern formation; IMP:TAIR.
DR InterPro; IPR009768; MAP70.
DR PANTHER; PTHR31246; PTHR31246; 1.
DR Pfam; PF07058; MAP70; 2.
PE 1: Evidence at protein level;
KW Cell wall biogenesis/degradation; Coiled coil; Cytoplasm; Cytoskeleton;
KW Microtubule; Reference proteome.
FT CHAIN 1..513
FT /note="Microtubule-associated protein 70-5"
FT /id="PRO_0000409461"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..400
FT /note="Required for targeting to microtubules"
FT /evidence="ECO:0000250"
FT REGION 347..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 10..322
FT /evidence="ECO:0000255"
FT COILED 426..501
FT /evidence="ECO:0000255"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..413
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 58521 MW; 22F26F264ADEF623 CRC64;
MTAAENPFVS DTSSLQSQLK EKEKELLAAK AEVEALRTNE ELKDRVFKEL RENVRKLEEK
LGATENQVDQ KELERKKLEE EKEDALAAQD AAEEALRRVY THQQDDDSLP LESIIAPLES
QIKIHKHEIS ALQEDKKALE RLTKSKESAL LEAERILRSA LERALIVEEV QNHNFELRRQ
IEICQDENKF LEKINRQKVL EIEKLSQSIV ELEEAILAGG TAANAVRDYR RQISQLNDEK
RTLERELARV KVSASRVALA VANEWKDEND RVMPVKQWLE ERRILHGEMQ KLKDKLAVSE
RTAKAESQLK ERLKLRLKTI EDGLKGPNTF FVSPTTKTEK SGKILGFLTS GGGSKKRSSS
QLRGSVTGRI HAMNQPIDRV GESDEMENSK ITANGLTDQH EEDSERKTEE DGNVYSEDMV
SGFLYDRLQK EVIALRKLCE SKEGTINAKN EEIKMLLKKV DALTKAIEVE TKKAKREAAA
REKENALAML NEESKLCRKA KLPRSRIPNP RCQ
