ID   MP70_MYCTO              Reviewed;         193 AA.
AC   P9WNF4; L0TDT6; P0A668; Q48934; Q48946; Q48947; Q48948; Q50656; Q50769;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 31.
DE   RecName: Full=Immunogenic protein MPT70;
DE   Flags: Precursor;
GN   Name=mpt70; OrderedLocusNames=MT2943;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBUNIT: Generally found as a monomer; homodimer in culture fluids.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; AE000516; AAK47268.1; -; Genomic_DNA.
DR   PIR; F70923; F70923.
DR   RefSeq; WP_003414644.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WNF4; -.
DR   SMR; P9WNF4; -.
DR   EnsemblBacteria; AAK47268; AAK47268; MT2943.
DR   GeneID; 45426864; -.
DR   KEGG; mtc:MT2943; -.
DR   PATRIC; fig|83331.31.peg.3180; -.
DR   HOGENOM; CLU_031281_3_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.30.180.10; -; 1.
DR   InterPro; IPR036378; FAS1_dom_sf.
DR   InterPro; IPR000782; FAS1_domain.
DR   Pfam; PF02469; Fasciclin; 1.
DR   SMART; SM00554; FAS1; 1.
DR   SUPFAM; SSF82153; SSF82153; 1.
DR   PROSITE; PS50213; FAS1; 1.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000250"
FT   CHAIN           31..193
FT                   /note="Immunogenic protein MPT70"
FT                   /id="PRO_0000427136"
FT   DOMAIN          57..189
FT                   /note="FAS1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00082"
SQ   SEQUENCE   193 AA;  19073 MW;  228695731C3FFB00 CRC64;
     MKVKNTIAAT SFAAAGLAAL AVAVSPPAAA GDLVGPGCAE YAAANPTGPA SVQGMSQDPV
     AVAASNNPEL TTLTAALSGQ LNPQVNLVDT LNSGQYTVFA PTNAAFSKLP ASTIDELKTN
     SSLLTSILTY HVVAGQTSPA NVVGTRQTLQ GASVTVTGQG NSLKVGNADV VCGGVSTANA
     TVYMIDSVLM PPA