MPA43_YEAST
ID MPA43_YEAST Reviewed; 542 AA.
AC P53583; D6W0U4;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Protein MPA43;
GN Name=MPA43; OrderedLocusNames=YNL249C; ORFNames=N0875;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 96604 / S288c / FY1679;
RX PubMed=9234673;
RX DOI=10.1002/(sici)1097-0061(199707)13:9<849::aid-yea106>3.0.co;2-n;
RA Sen-Gupta M., Gueldener U., Beinhauer J.D., Fiedler T.A., Hegemann J.H.;
RT "Sequence analysis of the 33 kb long region between ORC5 and SUI1 from the
RT left arm of chromosome XIV from Saccharomyces cerevisiae.";
RL Yeast 13:849-860(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169873;
RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K.,
RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K.,
RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M.,
RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F.,
RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., Doignon F.,
RA Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., Fritz C.,
RA Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., Goffeau A.,
RA Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., Hilbert H.,
RA Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., Jonniaux J.-L.,
RA Karpfinger-Hartl L., Lanfranchi G., Lepingle A., Levesque H., Lyck R.,
RA Maftahi M., Mallet L., Maurer C.T.C., Messenguy F., Mewes H.-W., Moestl D.,
RA Nasr F., Nicaud J.-M., Niedenthal R.K., Pandolfo D., Pierard A.,
RA Piravandi E., Planta R.J., Pohl T.M., Purnelle B., Rebischung C.,
RA Remacha M.A., Revuelta J.L., Rinke M., Saiz J.E., Sartorello F.,
RA Scherens B., Sen-Gupta M., Soler-Mira A., Urbanus J.H.M., Valle G.,
RA Van Dyck L., Verhasselt P., Vierendeels F., Vissers S., Voet M.,
RA Volckaert G., Wach A., Wambutt R., Wedler H., Zollner A., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
RT evolutionary implications.";
RL Nature 387:93-98(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-542.
RC STRAIN=ENY.WA-1A;
RA Boles E., Hettmann C., Zimmermann F.K.;
RL Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- MISCELLANEOUS: Present with 1050 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X96722; CAA65495.1; -; Genomic_DNA.
DR EMBL; Z71525; CAA96156.1; -; Genomic_DNA.
DR EMBL; AY723861; AAU09778.1; -; Genomic_DNA.
DR EMBL; X94214; CAA63905.1; -; Genomic_DNA.
DR EMBL; BK006947; DAA10310.1; -; Genomic_DNA.
DR PIR; S63222; S63222.
DR RefSeq; NP_014150.1; NM_001183087.1.
DR AlphaFoldDB; P53583; -.
DR SMR; P53583; -.
DR BioGRID; 35590; 42.
DR IntAct; P53583; 25.
DR STRING; 4932.YNL249C; -.
DR MaxQB; P53583; -.
DR PaxDb; P53583; -.
DR PRIDE; P53583; -.
DR EnsemblFungi; YNL249C_mRNA; YNL249C; YNL249C.
DR GeneID; 855472; -.
DR KEGG; sce:YNL249C; -.
DR SGD; S000005193; MPA43.
DR VEuPathDB; FungiDB:YNL249C; -.
DR eggNOG; KOG2517; Eukaryota.
DR GeneTree; ENSGT01000000214434; -.
DR HOGENOM; CLU_009281_10_3_1; -.
DR InParanoid; P53583; -.
DR OMA; NVVFWMD; -.
DR BioCyc; YEAST:G3O-33246-MON; -.
DR PRO; PR:P53583; -.
DR Proteomes; UP000002311; Chromosome XIV.
DR RNAct; P53583; protein.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR GO; GO:0019150; F:D-ribulokinase activity; IBA:GO_Central.
DR GO; GO:0046835; P:carbohydrate phosphorylation; IBA:GO_Central.
DR GO; GO:0019321; P:pentose metabolic process; IBA:GO_Central.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018485; Carb_kinase_FGGY_C.
DR InterPro; IPR018484; Carb_kinase_FGGY_N.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..542
FT /note="Protein MPA43"
FT /id="PRO_0000096549"
FT CONFLICT 46..53
FT /note="KKSWKFWQ -> RSHGNLA (in Ref. 5; CAA63905)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 542 AA; 61667 MW; 830AA8D4E95365AD CRC64;
MNSSLQVGIG IDVGSSSARI GVYNYYNDAL LEMAQEPVPY YQDSSKKSWK FWQKSTEIIK
ALQKCLQKLN IREYEVKSCG VSATCSLAIF ERDRTSNMLI PYPNEDNVIF WMDSSAVNEC
QWLNMQCPQQ LLDYLGGKFV PEMGVPKLKY FLDEYSHLRD KHFHIFDLHQ YIAYELSRLY
EWNIEGLLGR ENLNGIGNDG EVSGWSSSFY KNIINLPSNV SIGTTSLVAN KHISTTVVRS
CIDSYASWFA VASPHLETSL FMIAGTSSCY MYGTTISDTR IPGVWGPFDT ILDNRGDFSV
YAAGQSCTGK LIEHLFESHP CARKILKDGA DIYQVLEQTI RDIEKNNGLS IHILTKDMFF
YGDYEGNRTP FADPRIKGSF IGESTDTSML NLTYKYICIL EFLSFQTKLI IDTFQNENSN
IHIKELRISG SQAKNERLLS LISLVNNGVA IIKPKENVDM MGIKGAYVLA KSAKEKKQLA
DVITERDISN DSEKFESLAE YRLGNDSILL RKLLCVKYHI HLDMAKQQKR YHKLVDEVFQ
HL
