MPA5A_AMBPS
ID MPA5A_AMBPS Reviewed; 77 AA.
AC P43174;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 57.
DE RecName: Full=Pollen allergen Amb p 5a;
DE AltName: Full=Allergen Amb p Va;
DE AltName: Allergen=Amb p 5a;
DE Flags: Precursor;
OS Ambrosia psilostachya (Western ragweed) (Ambrosia coronopifolia).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC Heliantheae alliance; Heliantheae; Ambrosia.
OX NCBI_TaxID=29715;
RN [1]
RP NUCLEOTIDE SEQUENCE, AND PROTEIN SEQUENCE OF 23-63.
RC TISSUE=Pollen;
RX PubMed=7511632;
RA Ghosh B., Rafnar T., Perry M.P., Bassolino-Klimas D., Metzler W.J.,
RA Klapper D.G., Marsh D.G.;
RT "Immunologic and molecular characterization of Amb p V allergens from
RT Ambrosia psilostachya (western Ragweed) pollen.";
RL J. Immunol. 152:2882-2889(1994).
CC -!- ALLERGEN: Causes an allergic reaction in human.
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DR EMBL; L24465; AAA20065.1; -; Unassigned_DNA.
DR EMBL; L24466; AAA20067.1; -; Unassigned_DNA.
DR AlphaFoldDB; P43174; -.
DR SMR; P43174; -.
DR Allergome; 3072; Amb p 5.0101.
DR Allergome; 31; Amb p 5.
DR InterPro; IPR005611; Amb_V_allergen.
DR InterPro; IPR036712; Amb_V_allergen_sf.
DR Pfam; PF03913; Ragweed_pollen; 1.
DR PIRSF; PIRSF002697; Amb_V_allergen; 1.
DR SMART; SM00816; Amb_V_allergen; 1.
DR SUPFAM; SSF57296; SSF57296; 1.
PE 1: Evidence at protein level;
KW Allergen; Direct protein sequencing; Disulfide bond; Signal.
FT SIGNAL 1..22
FT /evidence="ECO:0000269|PubMed:7511632"
FT CHAIN 23..77
FT /note="Pollen allergen Amb p 5a"
FT /id="PRO_0000021742"
FT DISULFID 26..61
FT /evidence="ECO:0000250"
FT DISULFID 33..48
FT /evidence="ECO:0000250"
FT DISULFID 40..54
FT /evidence="ECO:0000250"
FT DISULFID 41..65
FT /evidence="ECO:0000250"
FT VARIANT 59
FT /note="E -> K (in clone A3)"
SQ SEQUENCE 77 AA; 8710 MW; 2D8976EB65D9A00F CRC64;
MNNEKNVSFE FIGSTDEVDE IKLLPCAWAG NVCGEKRAYC CSDPGRYCPW QVVCYESSEI
CSQKCGKMRM NVTKNTI