ID   MPA5A_LOLPR             Reviewed;         307 AA.
AC   Q40240;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 2.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Major pollen allergen Lol p 5a;
DE   AltName: Full=Allergen Lol p Ib;
DE   AltName: Full=Allergen Lol p Va;
DE   AltName: Allergen=Lol p 5a;
DE   Flags: Precursor;
GN   Name=LOLPIB;
OS   Lolium perenne (Perennial ryegrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Poodae; Poeae; Poeae Chloroplast Group 2 (Poeae type); Loliinae;
OC   Lolium.
OX   NCBI_TaxID=4522;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1671715; DOI=10.1073/pnas.88.4.1384;
RA   Singh M.B., Hough T., Theerakulpisut P., Avjioglu A., Davies S.,
RA   Smith P.M., Taylor P., Simpson R.J., Ward L.D., McCluskey J., Puy R.,
RA   Knox R.B.;
RT   "Isolation of cDNA encoding a newly identified major allergenic protein of
RT   rye-grass pollen: intracellular targeting to the amyloplast.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:1384-1388(1991).
CC   -!- SUBCELLULAR LOCATION: Note=Starch granule.
CC   -!- TISSUE SPECIFICITY: Pollen, starch granules.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Causes grass pollen
CC       allergy.
CC   -!- SIMILARITY: Belongs to the Poa p IX/Phl p VI allergen family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA33406.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; M59163; AAA33406.1; ALT_FRAME; mRNA.
DR   PIR; A38582; A38582.
DR   AlphaFoldDB; Q40240; -.
DR   SMR; Q40240; -.
DR   Allergome; 460; Lol p 5.
DR   Allergome; 462; Lol p 5.0102.
DR   Gene3D; 1.20.120.320; -; 2.
DR   InterPro; IPR002914; Poa_pIX/Phl_pVI.
DR   InterPro; IPR035506; Pollen_allergen/Os.
DR   Pfam; PF01620; Pollen_allerg_2; 1.
DR   SUPFAM; SSF81736; SSF81736; 2.
PE   1: Evidence at protein level;
KW   Allergen; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..307
FT                   /note="Major pollen allergen Lol p 5a"
FT                   /id="PRO_0000021743"
SQ   SEQUENCE   307 AA;  30887 MW;  926645E57F1B6952 CRC64;
     MAVQKYTVAL FLAVALVAGP AASYAADAGY TPAAAATPAT PAATPAAAGG KATTDEQKLL
     EDVNAGFKAA VAAAANAPPA DKFKIFEAAF SESSKGLLAT SAAKAPGLIP KLDTAYDVAY
     KAAEATPEAK YDAFVTALTE ALRVIAGALE VHAVKPATEE VLAAKIPTGE LQIVDKIDAA
     FKIAATAANA APTNDKFTVF ESAFNKALNE CTGGAYETYK FIPSLEAAVK QAYAATVAAA
     PEVKYAVFEA ALTKAITAMT QAQKAGKPAA AAATAAATVA TAAATAAAVL PPPLLVVQSL
     ISLLIYY