MPA5A_PHLPR
ID MPA5A_PHLPR Reviewed; 286 AA.
AC Q40962;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 15-JUL-1998, sequence version 2.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Pollen allergen Phl p 5a;
DE AltName: Full=Allergen Phl p Va;
DE AltName: Allergen=Phl p 5a;
DE Flags: Fragment;
OS Phleum pratense (Common timothy).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Poodae; Poeae; Poeae Chloroplast Group 2 (Poeae type); Poinae;
OC Phleum.
OX NCBI_TaxID=15957;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Agrostideae;
RX PubMed=7520460; DOI=10.1016/0091-6749(94)90037-x;
RA Bufe A., Becker W.M., Schramm G., Petersen A., Mamat U., Schlaak M.;
RT "Major allergen Phl p Va (timothy grass) bears at least two different IgE-
RT reactive epitopes.";
RL J. Allergy Clin. Immunol. 94:173-181(1994).
RN [2]
RP SEQUENCE REVISION.
RA Bufe A.;
RL Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALLERGEN: Causes an allergic reaction in human. Causes grass pollen
CC allergy.
CC -!- SIMILARITY: Belongs to the Poa p IX/Phl p VI allergen family.
CC {ECO:0000305}.
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DR EMBL; X70942; CAA50281.1; -; mRNA.
DR AlphaFoldDB; Q40962; -.
DR BMRB; Q40962; -.
DR SMR; Q40962; -.
DR Allergome; 558; Phl p 5.
DR Allergome; 560; Phl p 5.0102.
DR ABCD; Q40962; 19 sequenced antibodies.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.120.320; -; 2.
DR InterPro; IPR002914; Poa_pIX/Phl_pVI.
DR InterPro; IPR035506; Pollen_allergen/Os.
DR Pfam; PF01620; Pollen_allerg_2; 1.
DR SUPFAM; SSF81736; SSF81736; 2.
PE 1: Evidence at protein level;
KW Allergen; Secreted.
FT CHAIN <1..286
FT /note="Pollen allergen Phl p 5a"
FT /id="PRO_0000096551"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 286 AA; 28530 MW; C0E12BE83A3070F5 CRC64;
ADLGYGPATP AAPAAGYTPA TPAAPAGADA AGKATTEEQK LIEKINAGFK AALAGAGVQP
ADKYRTFVAT FGPASNKAFA EGLSGEPKGA AESSSKAALT SKLDAAYKLA YKTAEGATPE
AKYDAYVATL SEALRIIAGT LEVHAVKPAA EEVKVIPAGE LQVIEKVDAA FKVAATAANA
APANDKFTVF EAAFNDEIKA STGGAYESYK FIPALEAAVK QAYAATVATA PEVKYTVFET
ALKKAITAMS EAQKAAKPAA AATATATAAV GAATGAATAA TGGYKV