ID   MPA5B_AMBPS             Reviewed;          77 AA.
AC   P43175;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Pollen allergen Amb p 5b;
DE   AltName: Full=Allergen Amb p Vb;
DE   AltName: Allergen=Amb p 5b;
DE   Flags: Precursor;
OS   Ambrosia psilostachya (Western ragweed) (Ambrosia coronopifolia).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Heliantheae; Ambrosia.
OX   NCBI_TaxID=29715;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Pollen;
RX   PubMed=7511632;
RA   Ghosh B., Rafnar T., Perry M.P., Bassolino-Klimas D., Metzler W.J.,
RA   Klapper D.G., Marsh D.G.;
RT   "Immunologic and molecular characterization of Amb p V allergens from
RT   Ambrosia psilostachya (western Ragweed) pollen.";
RL   J. Immunol. 152:2882-2889(1994).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
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DR   EMBL; L24467; AAA20064.1; -; Unassigned_DNA.
DR   EMBL; L24468; AAA20066.1; -; Unassigned_DNA.
DR   EMBL; L24469; AAA20068.1; -; Unassigned_DNA.
DR   AlphaFoldDB; P43175; -.
DR   SMR; P43175; -.
DR   Allergome; 3073; Amb p 5.0201.
DR   Allergome; 31; Amb p 5.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.160.80; -; 1.
DR   InterPro; IPR005611; Amb_V_allergen.
DR   InterPro; IPR036712; Amb_V_allergen_sf.
DR   Pfam; PF03913; Ragweed_pollen; 1.
DR   PIRSF; PIRSF002697; Amb_V_allergen; 1.
DR   SMART; SM00816; Amb_V_allergen; 1.
DR   SUPFAM; SSF57296; SSF57296; 1.
PE   1: Evidence at protein level;
KW   Allergen; Disulfide bond; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..77
FT                   /note="Pollen allergen Amb p 5b"
FT                   /id="PRO_0000021744"
FT   DISULFID        26..61
FT                   /evidence="ECO:0000250"
FT   DISULFID        33..48
FT                   /evidence="ECO:0000250"
FT   DISULFID        40..54
FT                   /evidence="ECO:0000250"
FT   VARIANT         40
FT                   /note="C -> S (in clone B2)"
FT   VARIANT         41..43
FT                   /note="SSD -> CTN (in clone B3)"
SQ   SEQUENCE   77 AA;  8641 MW;  5FB321DB46AB4560 CRC64;
     MNNEKNVSFE FIGSTNEVDE IKVMACYAAG SICGEKRGYC SSDPGRYCPW QVVCYESRKI
     CAKNAAKMRM NVTKNTI