MPA5B_LOLPR
ID MPA5B_LOLPR Reviewed; 339 AA.
AC Q40237;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Major pollen allergen Lol p 5b;
DE AltName: Full=Allergen Lol p Vb;
DE AltName: Allergen=Lol p 5b;
DE Flags: Precursor;
OS Lolium perenne (Perennial ryegrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Pooideae; Poodae; Poeae; Poeae Chloroplast Group 2 (Poeae type); Loliinae;
OC Lolium.
OX NCBI_TaxID=4522;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Pollen;
RX PubMed=8262382; DOI=10.1016/0378-1119(93)90099-o;
RA Ong E.K., Griffith I.J., Knox R.B., Singh M.B.;
RT "Cloning of a cDNA encoding a group-V (group-IX) allergen isoform from rye-
RT grass pollen that demonstrates specific antigenic immunoreactivity.";
RL Gene 134:235-240(1993).
CC -!- SUBCELLULAR LOCATION: Note=Starch granule. {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Pollen, starch granules.
CC -!- ALLERGEN: Causes an allergic reaction in human. Causes grass pollen
CC allergy.
CC -!- SIMILARITY: Belongs to the Poa p IX/Phl p VI allergen family.
CC {ECO:0000305}.
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DR EMBL; L13083; AAA33405.1; -; mRNA.
DR PIR; JT0756; JT0756.
DR AlphaFoldDB; Q40237; -.
DR SMR; Q40237; -.
DR Allergome; 460; Lol p 5.
DR Allergome; 461; Lol p 5.0101.
DR Gene3D; 1.20.120.320; -; 2.
DR InterPro; IPR002914; Poa_pIX/Phl_pVI.
DR InterPro; IPR035506; Pollen_allergen/Os.
DR Pfam; PF01620; Pollen_allerg_2; 2.
DR SUPFAM; SSF81736; SSF81736; 2.
PE 1: Evidence at protein level;
KW Allergen; Repeat; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..339
FT /note="Major pollen allergen Lol p 5b"
FT /id="PRO_0000021745"
FT REPEAT 32..34
FT /note="1-1"
FT REPEAT 35..37
FT /note="1-2"
FT REPEAT 38..40
FT /note="1-3"
FT REPEAT 41..43
FT /note="1-4"
FT REPEAT 44..46
FT /note="1-5"
FT REPEAT 47..49
FT /note="1-6"
FT REPEAT 50..52
FT /note="1-7"
FT REPEAT 53..55
FT /note="1-8"
FT REPEAT 56..58
FT /note="1-9"
FT REPEAT 285..290
FT /note="2-1; truncated"
FT REPEAT 292..300
FT /note="2-2"
FT REPEAT 301..309
FT /note="2-3"
FT REPEAT 310..318
FT /note="2-4"
FT REPEAT 319..327
FT /note="2-5"
FT REPEAT 328..334
FT /note="2-6; truncated"
FT REGION 32..58
FT /note="9 X 3 AA tandem repeats of [PA]-A-[TA]"
FT REGION 36..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 285..334
FT /note="6 X 9 AA approximate tandem repeats of T-A-T-A-T-P-
FT A-A-A"
SQ SEQUENCE 339 AA; 33750 MW; 3CAA3115625E0610 CRC64;
MAVQKHTVAL FLAVALVAGP AASYAADAGY APATPATPAA PATAATPATP ATPATPAAVP
SGKATTEEQK LIEKINAGFK AAVAAAAVVP PADKYKTFVE TFGTATNKAF VEGLASGYAD
QSKNQLTSKL DAALKLAYEA AQGATPEAKY DAYVATLTEA LRVIAGTLEV HAVKPAAEEV
KVGAIPAAEV QLIDKVDAAY RTAATAANAA PANDKFTVFE NTFNNAIKVS LGAAYDSYKF
IPTLVAAVKQ AYAAKQATAP EVKYTVSETA LKKAVTAMSE AEKEATPAAA ATATPTPAAA
TATATPAAAY ATATPAAATA TATPAAATAT PAAAGGYKV