ID   MPAA3_AMBEL             Reviewed;         101 AA.
AC   P00304;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Pollen allergen Amb a 3;
DE   AltName: Full=Allergen Amb a III;
DE   AltName: Full=Allergen Ra3;
DE   AltName: Allergen=Amb a 3;
OS   Ambrosia artemisiifolia var. elatior (Short ragweed) (Ambrosia elatior).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Heliantheae; Ambrosia.
OX   NCBI_TaxID=4215;
RN   [1]
RP   PROTEIN SEQUENCE, DISULFIDE BOND, AND GLYCOSYLATION AT ASN-41 AND SER-84.
RC   TISSUE=Pollen;
RX   PubMed=7459340; DOI=10.1021/bi00566a010;
RA   Klapper D.G., Goodfriend L., Capra J.D.;
RT   "Amino acid sequence of ragweed allergen Ra3.";
RL   Biochemistry 19:5729-5734(1980).
CC   -!- PTM: The identity of the saccharide is not reported (PubMed:7459340).
CC       The sugar attached to Ser-84 is represented simply as Hex.
CC       {ECO:0000269|PubMed:7459340}.
CC   -!- PTM: Cys-97 sulfhydryl group is modified but does not form an
CC       interchain disulfide bond. {ECO:0000269|PubMed:7459340}.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
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DR   PIR; A00313; ARRA3.
DR   AlphaFoldDB; P00304; -.
DR   SMR; P00304; -.
DR   Allergome; 27; Amb a 3.
DR   Allergome; 3068; Amb a 3.0101.
DR   iPTMnet; P00304; -.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   Gene3D; 2.60.40.420; -; 1.
DR   InterPro; IPR008972; Cupredoxin.
DR   InterPro; IPR039391; Phytocyanin.
DR   InterPro; IPR003245; Phytocyanin_dom.
DR   PANTHER; PTHR33021; PTHR33021; 1.
DR   Pfam; PF02298; Cu_bind_like; 1.
DR   SUPFAM; SSF49503; SSF49503; 1.
DR   PROSITE; PS51485; PHYTOCYANIN; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond; Glycoprotein.
FT   CHAIN           1..101
FT                   /note="Pollen allergen Amb a 3"
FT                   /id="PRO_0000085558"
FT   DOMAIN          2..101
FT                   /note="Phytocyanin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00818"
FT   MOD_RES         97
FT                   /note="Cysteine derivative"
FT   MOD_RES         101
FT                   /note="Blocked carboxyl end (Arg)"
FT   CARBOHYD        41
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000269|PubMed:7459340"
FT   CARBOHYD        84
FT                   /note="O-linked (Hex) serine"
FT                   /evidence="ECO:0000269|PubMed:7459340"
FT   DISULFID        61..88
FT                   /evidence="ECO:0000305|PubMed:7459340"
SQ   SEQUENCE   101 AA;  11375 MW;  3CBD6721B85C01DD CRC64;
     GKVYLVGGPE LGGWKLQSDP RAYALWSARQ QFKTTDVLWF NFTTGEDSVA EVWREEAYHA
     CDIKDPIRLE PGGPDRFTLL TPGSHFICTK DQKFVACVPG R