ID   MPAC1_CYNDA             Reviewed;         246 AA.
AC   O04701;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Major pollen allergen Cyn d 1;
DE   AltName: Allergen=Cyn d 1;
GN   Name=CYND1;
OS   Cynodon dactylon (Bermuda grass) (Panicum dactylon).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Chloridoideae; Cynodonteae; Eleusininae; Cynodon.
OX   NCBI_TaxID=28909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   TISSUE=Pollen;
RX   PubMed=8757211; DOI=10.1016/s0091-6749(96)70158-6;
RA   Smith P.M., Suphioglu C., Griffith I.J., Theriault K., Knox R.B.,
RA   Singh M.B.;
RT   "Cloning and expression in yeast Pichia pastoris of a biologically active
RT   form of Cyn d 1, the major allergen of Bermuda grass pollen.";
RL   J. Allergy Clin. Immunol. 98:331-343(1996).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Causes grass pollen
CC       allergy. Binds to IgE.
CC   -!- SIMILARITY: Belongs to the expansin family. Expansin B subfamily.
CC       {ECO:0000305}.
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DR   EMBL; S83343; AAB50734.2; -; mRNA.
DR   AlphaFoldDB; O04701; -.
DR   SMR; O04701; -.
DR   Allergome; 266; Cyn d 1.
DR   Allergome; 267; Cyn d 1.0101.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR   GO; GO:0019953; P:sexual reproduction; IEA:InterPro.
DR   Gene3D; 2.40.40.10; -; 1.
DR   Gene3D; 2.60.40.760; -; 1.
DR   InterPro; IPR007118; Expan_Lol_pI.
DR   InterPro; IPR007112; Expansin/allergen_DPBB_dom.
DR   InterPro; IPR007117; Expansin_CBD.
DR   InterPro; IPR036749; Expansin_CBD_sf.
DR   InterPro; IPR005795; LolPI.
DR   InterPro; IPR009009; RlpA-like_DPBB.
DR   InterPro; IPR036908; RlpA-like_sf.
DR   Pfam; PF03330; DPBB_1; 1.
DR   Pfam; PF01357; Expansin_C; 1.
DR   PRINTS; PR01225; EXPANSNFAMLY.
DR   PRINTS; PR00829; LOLP1ALLERGN.
DR   SMART; SM00837; DPBB_1; 1.
DR   SUPFAM; SSF49590; SSF49590; 1.
DR   SUPFAM; SSF50685; SSF50685; 1.
DR   PROSITE; PS50843; EXPANSIN_CBD; 1.
DR   PROSITE; PS50842; EXPANSIN_EG45; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Glycoprotein; Secreted.
FT   CHAIN           1..246
FT                   /note="Major pollen allergen Cyn d 1"
FT                   /id="PRO_0000154569"
FT   DOMAIN          39..145
FT                   /note="Expansin-like EG45"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00079"
FT   DOMAIN          159..240
FT                   /note="Expansin-like CBD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT   CARBOHYD        9
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   246 AA;  26889 MW;  43D8442DBA588322 CRC64;
     AIGDKPGPNI TATYGSKWLE ARATFYGSNP RGAAPDDHGG ACGYKDVDKP PFDGMTACGN
     EPIFKDGLGC RACYEIKCKE PVECSGEPVL VKITDKNYEH IAAYHFDLSG KAFGAMAKKG
     QEDKLRKAGE LTLQFRRVKC KYPSGTKITF HIEKGSNDHY LALLVKYAAG DGNIVAVDIK
     PRDSDEFIPM KSSWGAIWRI DPKKPLKGPF SIRLTSEGGA HLVQDDVIPA NWKPDTVYTS
     KLQFGA