ID   MPAL2_LOLPR             Reviewed;          97 AA.
AC   P14947;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Pollen allergen Lol p 2-A;
DE   AltName: Full=Allergen Lol p II-A;
DE   AltName: Allergen=Lol p 2-A;
OS   Lolium perenne (Perennial ryegrass).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Poodae; Poeae; Poeae Chloroplast Group 2 (Poeae type); Loliinae;
OC   Lolium.
OX   NCBI_TaxID=4522;
RN   [1]
RP   PROTEIN SEQUENCE, AND ALLERGEN.
RX   PubMed=2472390; DOI=10.1016/s0021-9258(18)60446-6;
RA   Ansari A.A., Shenbagamurthi P., Marsh D.G.;
RT   "Complete amino acid sequence of a Lolium perenne (perennial rye grass)
RT   pollen allergen, Lol p II.";
RL   J. Biol. Chem. 264:11181-11185(1989).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Causes grass pollen
CC       allergy. Binds to IgE. {ECO:0000269|PubMed:2472390}.
CC   -!- SIMILARITY: Belongs to the expansin family. Expansin B subfamily.
CC       {ECO:0000305}.
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DR   PIR; A34291; A34291.
DR   AlphaFoldDB; P14947; -.
DR   SMR; P14947; -.
DR   Allergome; 3355; Lol p 2.0101.
DR   Allergome; 457; Lol p 2.
DR   ABCD; P14947; 1 sequenced antibody.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.760; -; 1.
DR   InterPro; IPR005453; Allergen_Lolp2.
DR   InterPro; IPR007117; Expansin_CBD.
DR   InterPro; IPR036749; Expansin_CBD_sf.
DR   Pfam; PF01357; Expansin_C; 1.
DR   PRINTS; PR01637; LOLP2ALLERGN.
DR   SUPFAM; SSF49590; SSF49590; 1.
DR   PROSITE; PS50843; EXPANSIN_CBD; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Secreted.
FT   CHAIN           1..97
FT                   /note="Pollen allergen Lol p 2-A"
FT                   /id="PRO_0000154572"
FT   DOMAIN          15..96
FT                   /note="Expansin-like CBD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00078"
FT   VARIANT         29
FT                   /note="S -> A"
FT   VARIANT         49
FT                   /note="N -> D"
FT   VARIANT         59
FT                   /note="D -> E"
FT   VARIANT         76
FT                   /note="M -> E"
SQ   SEQUENCE   97 AA;  10880 MW;  91A7DDB5DEA5BDD7 CRC64;
     AAPVEFTVEK GSDEKNLALS IKYNKEGDSM AEVELKEHGS NEWLALKKNG DGVWEIKSDK
     PLKGPFNFRF VSEKGMRNVF DDVVPADFKV GTTYKPE