ID   MPAP6_PHLPR             Reviewed;         132 AA.
AC   P43215;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Pollen allergen Phl p 6;
DE   AltName: Full=Allergen Phl p VI;
DE   AltName: Allergen=Phl p 6;
DE   Flags: Precursor;
GN   Name=PHLPVI;
OS   Phleum pratense (Common timothy).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Poodae; Poeae; Poeae Chloroplast Group 2 (Poeae type); Poinae;
OC   Phleum.
OX   NCBI_TaxID=15957;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND ALLERGEN.
RC   STRAIN=cv. Agrostideae 24W28-7C;
RX   PubMed=7647586; DOI=10.1159/000237118;
RA   Petersen A., Bufe A., Schramm G., Schlaak M., Becker W.;
RT   "Characterization of the allergen group VI in timothy grass pollen (Phl p
RT   6). II. cDNA cloning of Phl p 6 and structural comparison to grass group
RT   V.";
RL   Int. Arch. Allergy Immunol. 108:55-59(1995).
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC       {ECO:0000269|PubMed:7647586}.
CC   -!- SIMILARITY: Belongs to the Poa p IX/Phl p VI allergen family.
CC       {ECO:0000305}.
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DR   EMBL; Z27082; CAA81608.1; -; mRNA.
DR   PIR; S38585; S38585.
DR   PDB; 1NLX; X-ray; 2.80 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N=23-132.
DR   PDB; 6TRK; X-ray; 1.60 A; A/B=23-132.
DR   PDBsum; 1NLX; -.
DR   PDBsum; 6TRK; -.
DR   AlphaFoldDB; P43215; -.
DR   SMR; P43215; -.
DR   Allergome; 3420; Phl p 6.0101.
DR   Allergome; 569; Phl p 6.
DR   ABCD; P43215; 5 sequenced antibodies.
DR   EvolutionaryTrace; P43215; -.
DR   Gene3D; 1.20.120.320; -; 1.
DR   InterPro; IPR002914; Poa_pIX/Phl_pVI.
DR   InterPro; IPR035506; Pollen_allergen/Os.
DR   Pfam; PF01620; Pollen_allerg_2; 1.
DR   SUPFAM; SSF81736; SSF81736; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Allergen; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..132
FT                   /note="Pollen allergen Phl p 6"
FT                   /id="PRO_0000021750"
FT   HELIX           24..45
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   TURN            46..49
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   HELIX           52..54
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   HELIX           55..77
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   HELIX           79..81
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   HELIX           82..98
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   HELIX           101..103
FT                   /evidence="ECO:0007829|PDB:6TRK"
FT   HELIX           104..120
FT                   /evidence="ECO:0007829|PDB:6TRK"
SQ   SEQUENCE   132 AA;  13921 MW;  3513D3D85069D5F8 CRC64;
     MVAMFLAVAV VLGLATSPTA EGGKATTEEQ KLIEDVNASF RAAMATTANV PPADKYKTFE
     AAFTVSSKRN LADAVSKAPQ LVPKLDEVYN AAYNAADHAA PEDKYEAFVL HFSEALRIIA
     GTPEVHAVKP GA