ID   MPCX_BOVIN              Reviewed;         181 AA.
AC   Q2M2T3;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=Mitochondrial pyruvate carrier-like protein;
DE   AltName: Full=Brain protein 44-like protein 2;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May mediate the uptake of pyruvate into mitochondria.
CC       {ECO:0000250|UniProtKB:P63030}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC       {ECO:0000250|UniProtKB:P63030}; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the mitochondrial pyruvate carrier (MPC) (TC
CC       2.A.105) family. {ECO:0000305}.
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DR   EMBL; BC111647; AAI11648.1; -; mRNA.
DR   RefSeq; NP_001069277.1; NM_001075809.2.
DR   AlphaFoldDB; Q2M2T3; -.
DR   STRING; 9913.ENSBTAP00000015642; -.
DR   PaxDb; Q2M2T3; -.
DR   GeneID; 520682; -.
DR   KEGG; bta:520682; -.
DR   CTD; 347411; -.
DR   eggNOG; KOG1590; Eukaryota.
DR   OrthoDB; 1584711at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0031305; C:integral component of mitochondrial inner membrane; IBA:GO_Central.
DR   GO; GO:0050833; F:pyruvate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006850; P:mitochondrial pyruvate transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR005336; MPC.
DR   Pfam; PF03650; MPC; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..181
FT                   /note="Mitochondrial pyruvate carrier-like protein"
FT                   /id="PRO_0000350553"
FT   TRANSMEM        23..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        52..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          125..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   181 AA;  19167 MW;  0ED407D3E38EFBCA CRC64;
     MAAVVALCRK AMETVKTKEF RDYLASTHFW GPVANWGLPL AAFRDMRASP DIISGRMTTA
     LIFYSMAFMR FAYRVQPRNL LLMACHGTNI VAQSMQAGRY LNYHYGGGTT AATTAAVSAA
     SATSTGSVDS SATSTGSVDS SATSTGSVDS SAATTPAAED PVAHSNCQEI TCCYLVTWDC
     D