6PGL_RHIME
ID 6PGL_RHIME Reviewed; 232 AA.
AC Q9Z3S1;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 24-OCT-2001, sequence version 2.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=6-phosphogluconolactonase;
DE Short=6PGL;
DE EC=3.1.1.31;
GN Name=pgl; Synonyms=devB; OrderedLocusNames=R00703; ORFNames=SMc03069;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=10400573; DOI=10.1128/jb.181.14.4176-4184.1999;
RA Willis L.B., Walker G.C.;
RT "A novel Sinorhizobium meliloti operon encodes an alpha-glucosidase and a
RT periplasmic-binding-protein-dependent transport system for alpha-
RT glucosides.";
RL J. Bacteriol. 181:4176-4184(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC 2/3.
CC -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC isomerase family. 6-phosphogluconolactonase subfamily. {ECO:0000305}.
CC -!- CAUTION: Seems to have a sequencing error in the C-terminal region when
CC compared to orthologs, but the potentially correct sequence could not
CC be inferred. {ECO:0000305}.
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DR EMBL; AF045609; AAD12044.1; -; Genomic_DNA.
DR EMBL; AL591688; CAC45275.1; -; Genomic_DNA.
DR RefSeq; NP_384809.1; NC_003047.1.
DR RefSeq; WP_003527053.1; NC_003047.1.
DR AlphaFoldDB; Q9Z3S1; -.
DR SMR; Q9Z3S1; -.
DR STRING; 266834.SMc03069; -.
DR EnsemblBacteria; CAC45275; CAC45275; SMc03069.
DR GeneID; 61602170; -.
DR KEGG; sme:SMc03069; -.
DR PATRIC; fig|266834.11.peg.2079; -.
DR eggNOG; COG0363; Bacteria.
DR HOGENOM; CLU_053947_2_1_5; -.
DR OMA; NDERWVD; -.
DR UniPathway; UPA00115; UER00409.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR CDD; cd01400; 6PGL; 1.
DR InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR039104; PGLS.
DR PANTHER; PTHR11054; PTHR11054; 1.
DR Pfam; PF01182; Glucosamine_iso; 1.
DR SUPFAM; SSF100950; SSF100950; 1.
DR TIGRFAMs; TIGR01198; pgl; 1.
PE 3: Inferred from homology;
KW Hydrolase; Reference proteome.
FT CHAIN 1..232
FT /note="6-phosphogluconolactonase"
FT /id="PRO_0000090105"
FT CONFLICT 184..227
FT /note="Missing (in Ref. 1; AAD12044)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 232 AA; 24408 MW; 5A29D02A62FCEED7 CRC64;
MSANMHIFEN PSALAEALAD DVGARLAAAI AARGTASLAV SGGSTPKAFF RSLSRRELDW
SKVTVTLVDE RFVPPENDRS NHRLVADNLL KDGAAEARFV PLYQAAETAE AAAAIASGRT
ASLGAPLDVV VLGMGTDGHT ASFFPGGTRL EEALDPTTPR GVITMEAEGA GEPRLTFTFS
SLQDAGYLVL HIEGSGKKEV LAQAEASGDE AEMPIRAMLR RAASPLQIYW AP
