ID   ARNE_ERWT9              Reviewed;         108 AA.
AC   B2VBI6;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE {ECO:0000255|HAMAP-Rule:MF_01869};
DE            Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnE {ECO:0000255|HAMAP-Rule:MF_01869};
DE   AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE {ECO:0000255|HAMAP-Rule:MF_01869};
GN   Name=arnE {ECO:0000255|HAMAP-Rule:MF_01869}; OrderedLocusNames=ETA_23780;
OS   Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB
OS   4357 / Et1/99).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=465817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99;
RX   PubMed=18462403; DOI=10.1111/j.1462-2920.2008.01639.x;
RA   Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R.,
RA   Geider K.;
RT   "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic
RT   bacterium in the genus Erwinia.";
RL   Environ. Microbiol. 10:2211-2222(2008).
CC   -!- FUNCTION: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
CC       (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the
CC       periplasmic side of the inner membrane. {ECO:0000255|HAMAP-
CC       Rule:MF_01869}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01869}.
CC   -!- SUBUNIT: Heterodimer of ArnE and ArnF. {ECO:0000255|HAMAP-
CC       Rule:MF_01869}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01869}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01869}.
CC   -!- SIMILARITY: Belongs to the ArnE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01869}.
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DR   EMBL; CU468135; CAO97424.1; -; Genomic_DNA.
DR   RefSeq; WP_012442092.1; NC_010694.1.
DR   AlphaFoldDB; B2VBI6; -.
DR   STRING; 465817.ETA_23780; -.
DR   EnsemblBacteria; CAO97424; CAO97424; ETA_23780.
DR   KEGG; eta:ETA_23780; -.
DR   eggNOG; COG2076; Bacteria.
DR   HOGENOM; CLU_131462_5_1_6; -.
DR   OMA; TCAGQLC; -.
DR   OrthoDB; 1944417at2; -.
DR   UniPathway; UPA00030; -.
DR   Proteomes; UP000001726; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:1901505; F:carbohydrate derivative transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR   HAMAP; MF_01869; Flippase_ArnE; 1.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR022883; Flippase_ArnE.
DR   InterPro; IPR000390; Small_drug/metabolite_transptr.
DR   PANTHER; PTHR30561; PTHR30561; 1.
DR   Pfam; PF00892; EamA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Lipid A biosynthesis;
KW   Lipid biosynthesis; Lipid metabolism; Lipopolysaccharide biosynthesis;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..108
FT                   /note="Probable 4-amino-4-deoxy-L-arabinose-
FT                   phosphoundecaprenol flippase subunit ArnE"
FT                   /id="PRO_0000382955"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
FT   TRANSMEM        58..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
FT   TRANSMEM        85..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
FT   DOMAIN          34..106
FT                   /note="EamA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
SQ   SEQUENCE   108 AA;  11739 MW;  782D7D0E985B0EB0 CRC64;
     MNILLIILAS LFSCAGQLCQ KQATTVSGGR RPLLLWLGGS VLLLGMAMLV WLRVLQTVPV
     GVAYPMLSLN FIFVTLAARW LWRETLSLRH ALGVILIVAG VAIMGSYT