MPM1_YEAST
ID MPM1_YEAST Reviewed; 252 AA.
AC P40364; D6VWB6;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 150.
DE RecName: Full=Mitochondrial peculiar membrane protein 1;
GN Name=MPM1; OrderedLocusNames=YJL066C; ORFNames=HRE252, J1111;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=7762302; DOI=10.1002/yea.320110108;
RA Vandenbol M., Durand P., Dion C., Portetelle D., Hilger F.;
RT "Sequence of a 17.1 kb DNA fragment from chromosome X of Saccharomyces
RT cerevisiae includes the mitochondrial ribosomal protein L8.";
RL Yeast 11:57-60(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8641269; DOI=10.1002/j.1460-2075.1996.tb00557.x;
RA Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C.,
RA Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D.,
RA Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J.,
RA Heumann K., Hilger F., Hollenberg C.P., Huang M.-E., Jacq C.,
RA Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E.,
RA Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T.,
RA Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R.,
RA Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N.,
RA To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H.,
RA von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.";
RL EMBO J. 15:2031-2049(1996).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP SUBCELLULAR LOCATION.
RX PubMed=11791739; DOI=10.1271/bbb.65.2577;
RA Inadome H., Noda Y., Adachi H., Yoda K.;
RT "A novel protein, Mpm1, of the mitochondria of the yeast Saccharomyces
RT cerevisiae.";
RL Biosci. Biotechnol. Biochem. 65:2577-2580(2001).
RN [5]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [6]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [7]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 76625 / YPH499;
RX PubMed=14576278; DOI=10.1073/pnas.2135385100;
RA Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E.,
RA Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P.,
RA Pfanner N., Meisinger C.;
RT "The proteome of Saccharomyces cerevisiae mitochondria.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003).
RN [8]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RX PubMed=22984289; DOI=10.1074/mcp.m112.021105;
RA Voegtle F.N., Burkhart J.M., Rao S., Gerbeth C., Hinrichs J.,
RA Martinou J.C., Chacinska A., Sickmann A., Zahedi R.P., Meisinger C.;
RT "Intermembrane space proteome of yeast mitochondria.";
RL Mol. Cell. Proteomics 11:1840-1852(2012).
CC -!- SUBCELLULAR LOCATION: Mitochondrion membrane
CC {ECO:0000269|PubMed:11791739, ECO:0000269|PubMed:14562095,
CC ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:22984289}; Peripheral
CC membrane protein {ECO:0000269|PubMed:11791739,
CC ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:14576278,
CC ECO:0000269|PubMed:22984289}; Intermembrane side
CC {ECO:0000269|PubMed:11791739, ECO:0000269|PubMed:14562095,
CC ECO:0000269|PubMed:14576278, ECO:0000269|PubMed:22984289}.
CC -!- MISCELLANEOUS: Present with 3390 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z34288; CAA84057.1; -; Genomic_DNA.
DR EMBL; Z49342; CAA89358.1; -; Genomic_DNA.
DR EMBL; BK006943; DAA08732.1; -; Genomic_DNA.
DR PIR; S50806; S50806.
DR RefSeq; NP_012469.3; NM_001181499.3.
DR AlphaFoldDB; P40364; -.
DR SMR; P40364; -.
DR BioGRID; 33688; 78.
DR DIP; DIP-3859N; -.
DR IntAct; P40364; 48.
DR MINT; P40364; -.
DR STRING; 4932.YJL066C; -.
DR MaxQB; P40364; -.
DR PaxDb; P40364; -.
DR PRIDE; P40364; -.
DR EnsemblFungi; YJL066C_mRNA; YJL066C; YJL066C.
DR GeneID; 853379; -.
DR KEGG; sce:YJL066C; -.
DR SGD; S000003602; MPM1.
DR VEuPathDB; FungiDB:YJL066C; -.
DR eggNOG; ENOG502RZT3; Eukaryota.
DR HOGENOM; CLU_1111888_0_0_1; -.
DR InParanoid; P40364; -.
DR OMA; XTAVEPL; -.
DR BioCyc; YEAST:G3O-31527-MON; -.
DR PRO; PR:P40364; -.
DR Proteomes; UP000002311; Chromosome X.
DR RNAct; P40364; protein.
DR GO; GO:0019898; C:extrinsic component of membrane; IDA:SGD.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IDA:SGD.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IDA:SGD.
DR InterPro; IPR035187; Mpm1.
DR Pfam; PF17234; MPM1; 1.
PE 1: Evidence at protein level;
KW Membrane; Mitochondrion; Reference proteome.
FT CHAIN 1..252
FT /note="Mitochondrial peculiar membrane protein 1"
FT /id="PRO_0000203056"
FT REGION 230..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 252 AA; 28470 MW; CC0E9E00D69E2FE7 CRC64;
MGFYEGDDND ANTKAFNDKY IKDQKFATAP FWNLFPKLRD IDEYDNPLLP LPFNFNFRDL
GDSALAMASG IPTVKQFDKC EELKGQSAWT TQGIWKCLVP SKAIPPLPQL DFLLPLEEIK
SDKSHSHGLF FNDFNLFLKW RSHMNRLQKQ RIKTRSTAVE PLARTPEDLM LNWDDLHLGN
DAEYASADGS KKIVGRAQSI STTKDSNDAK PSTVKTEKIY FDDGTVDITT TTTSKGSSPQ
VKHKVVSVDE DN
