ARNE_PSEFS
ID ARNE_PSEFS Reviewed; 115 AA.
AC C3KAC9;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE {ECO:0000255|HAMAP-Rule:MF_01869};
DE Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnE {ECO:0000255|HAMAP-Rule:MF_01869};
DE AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE {ECO:0000255|HAMAP-Rule:MF_01869};
GN Name=arnE {ECO:0000255|HAMAP-Rule:MF_01869}; OrderedLocusNames=PFLU_3038;
OS Pseudomonas fluorescens (strain SBW25).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=216595;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SBW25;
RX PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA Jackson R.W., Preston G.M., Zhang X.-X., Moon C.D., Gehrig S.M.,
RA Godfrey S.A.C., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT "Genomic and genetic analyses of diversity and plant interactions of
RT Pseudomonas fluorescens.";
RL Genome Biol. 10:R51.1-R51.16(2009).
CC -!- FUNCTION: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
CC (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the
CC periplasmic side of the inner membrane. {ECO:0000255|HAMAP-
CC Rule:MF_01869}.
CC -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01869}.
CC -!- SUBUNIT: Heterodimer of ArnE and ArnF. {ECO:0000255|HAMAP-
CC Rule:MF_01869}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01869}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01869}.
CC -!- SIMILARITY: Belongs to the ArnE family. {ECO:0000255|HAMAP-
CC Rule:MF_01869}.
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DR EMBL; AM181176; CAY49267.1; -; Genomic_DNA.
DR RefSeq; WP_012724218.1; NC_012660.1.
DR AlphaFoldDB; C3KAC9; -.
DR SMR; C3KAC9; -.
DR STRING; 216595.PFLU_3038; -.
DR EnsemblBacteria; CAY49267; CAY49267; PFLU_3038.
DR KEGG; pfs:PFLU_3038; -.
DR eggNOG; COG2076; Bacteria.
DR HOGENOM; CLU_131462_5_1_6; -.
DR OMA; TCAGQLC; -.
DR OrthoDB; 1944417at2; -.
DR UniPathway; UPA00030; -.
DR Proteomes; UP000002332; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:1901505; F:carbohydrate derivative transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR HAMAP; MF_01869; Flippase_ArnE; 1.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR022883; Flippase_ArnE.
DR InterPro; IPR000390; Small_drug/metabolite_transptr.
DR PANTHER; PTHR30561; PTHR30561; 1.
DR Pfam; PF00892; EamA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Lipid A biosynthesis;
KW Lipid biosynthesis; Lipid metabolism; Lipopolysaccharide biosynthesis;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..115
FT /note="Probable 4-amino-4-deoxy-L-arabinose-
FT phosphoundecaprenol flippase subunit ArnE"
FT /id="PRO_0000382987"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
FT DOMAIN 44..113
FT /note="EamA"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01869"
SQ SEQUENCE 115 AA; 12859 MW; 4FD758E60C7E0365 CRC64;
MITLLLLLAA CLLTCMGQVS QKFAVESWRD LPEGWALKLR SPWLWSALVC LGLGLLVWLL
VLQRLEVGIA YPMLSLNFVL VTLVARFVFH EPIDARHWLG VALVISGVVL LGRHV