MPV17_CAEBR
ID MPV17_CAEBR Reviewed; 181 AA.
AC Q60SZ2; A8XYE1;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 25-MAY-2022, entry version 70.
DE RecName: Full=Mpv17-like protein;
DE Flags: Fragment;
GN ORFNames=CBG20693;
OS Caenorhabditis briggsae.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6238;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AF16;
RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA Durbin R.M., Waterston R.H.;
RT "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT genomics.";
RL PLoS Biol. 1:166-192(2003).
CC -!- FUNCTION: Involved in mitochondria homeostasis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC {ECO:0000305}.
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DR EMBL; HE600991; CAP37658.3; -; Genomic_DNA.
DR AlphaFoldDB; Q60SZ2; -.
DR STRING; 6238.CBG20693; -.
DR WormBase; CBG20693; CBP11667; WBGene00039629; -.
DR eggNOG; KOG1944; Eukaryota.
DR HOGENOM; CLU_049109_8_3_1; -.
DR InParanoid; Q60SZ2; -.
DR OMA; ANIHTED; -.
DR OrthoDB; 1324608at2759; -.
DR Proteomes; UP000008549; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007248; Mpv17_PMP22.
DR PANTHER; PTHR11266; PTHR11266; 1.
DR Pfam; PF04117; Mpv17_PMP22; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..>181
FT /note="Mpv17-like protein"
FT /id="PRO_0000234402"
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 48..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT NON_TER 181
SQ SEQUENCE 181 AA; 21036 MW; 943392B6EDD05B2B CRC64;
MNLLRTFNAT LARRPLATQV IVSGAVCGAG DAFTQYLTGQ KSWDYKRTAR FTCLAAVFIA
PPLNVWFRVL ERVRHSNRHA QVFSRMSIDQ FMFSPFFNAI ILVNLRLLEG FSFSKSVDKM
KNDWYDVYTS SLRLWPAVQL INFYFVPLNY RVILIQVVAF FWNSWLSFKT QTPALEDPTI
E