MPV17_CAEEL
ID MPV17_CAEEL Reviewed; 181 AA.
AC Q7YWV6;
DT 16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Mpv17-like protein;
GN ORFNames=T18D3.9;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Involved in mitochondria homeostasis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC {ECO:0000305}.
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DR EMBL; Z68119; CAE17916.1; -; Genomic_DNA.
DR RefSeq; NP_001024916.1; NM_001029745.1.
DR AlphaFoldDB; Q7YWV6; -.
DR STRING; 6239.T18D3.9; -.
DR PaxDb; Q7YWV6; -.
DR EnsemblMetazoa; T18D3.9.1; T18D3.9.1; WBGene00011826.
DR EnsemblMetazoa; T18D3.9.2; T18D3.9.2; WBGene00011826.
DR GeneID; 3564939; -.
DR KEGG; cel:CELE_T18D3.9; -.
DR UCSC; T18D3.9; c. elegans.
DR CTD; 3564939; -.
DR WormBase; T18D3.9; CE35017; WBGene00011826; -.
DR eggNOG; KOG1944; Eukaryota.
DR GeneTree; ENSGT00940000160891; -.
DR HOGENOM; CLU_049109_8_3_1; -.
DR InParanoid; Q7YWV6; -.
DR OMA; TDTNKDA; -.
DR OrthoDB; 1324608at2759; -.
DR PhylomeDB; Q7YWV6; -.
DR Reactome; R-CEL-9033241; Peroxisomal protein import.
DR PRO; PR:Q7YWV6; -.
DR Proteomes; UP000001940; Chromosome X.
DR Bgee; WBGene00011826; Expressed in embryo and 3 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007248; Mpv17_PMP22.
DR PANTHER; PTHR11266; PTHR11266; 1.
DR Pfam; PF04117; Mpv17_PMP22; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..181
FT /note="Mpv17-like protein"
FT /id="PRO_0000234403"
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..169
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 181 AA; 21308 MW; AEABB9EF70F844C2 CRC64;
MVIILFIRRR LATNPLSTQM CIAGTISGSG DCLAQYLSHN QEWDRWRTAR FSFLSSCFMA
PSLFIWFRLL EKVKGNNKSL LLVKKLCIDQ LCFSPCFNAA ILFNLRLLQH QSAEKSWDLL
KEDWFNIYAT SLKVWPFVQV VNLCFVPLNY RVILNQVVAF FWNCYLSYIT QKPIDHIEQF
Y