ID   MP_PINMG                Reviewed;         254 AA.
AC   H2A0K7;
DT   13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   25-MAY-2022, entry version 15.
DE   RecName: Full=Mantle protein {ECO:0000250|UniProtKB:P86948};
DE            Short=MP {ECO:0000250|UniProtKB:P86948};
DE   Flags: Precursor;
OS   Margaritifera margaritifera (Freshwater pearl mussel).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Pterioida; Pterioidea; Pteriidae; Pinctada.
OX   NCBI_TaxID=102329;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], AND IDENTIFICATION.
RC   TISSUE=Mantle;
RX   PubMed=21040589; DOI=10.1186/1471-2164-11-613;
RA   Joubert C., Piquemal D., Marie B., Manchon L., Pierrat F.,
RA   Zanella-Cleon I., Cochennec-Laureau N., Gueguen Y., Montagnani C.;
RT   "Transcriptome and proteome analysis of Pinctada margaritifera calcifying
RT   mantle and shell: focus on biomineralization.";
RL   BMC Genomics 11:613-613(2010).
RN   [2]
RP   PROTEIN SEQUENCE OF 35-42; 61-70; 119-126; 129-140 AND 217-229, SUBCELLULAR
RP   LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Shell;
RX   PubMed=23213212; DOI=10.1073/pnas.1210552109;
RA   Marie B., Joubert C., Tayale A., Zanella-Cleon I., Belliard C.,
RA   Piquemal D., Cochennec-Laureau N., Marin F., Gueguen Y., Montagnani C.;
RT   "Different secretory repertoires control the biomineralization processes of
RT   prism and nacre deposition of the pearl oyster shell.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:20986-20991(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23213212}.
CC   -!- TISSUE SPECIFICITY: Prismatic layer of shell (at protein level).
CC       Expressed primarily in the mantle with highest level in the outer
CC       epithelium of the mantle edge and lower level in the mantle pallium.
CC       {ECO:0000269|PubMed:23213212}.
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DR   EMBL; HE610374; CCE46148.1; -; mRNA.
DR   AlphaFoldDB; H2A0K7; -.
DR   SMR; H2A0K7; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..254
FT                   /note="Mantle protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000417977"
SQ   SEQUENCE   254 AA;  28945 MW;  C399DB8B9A69C6B2 CRC64;
     MLAVLLFAAL VATAYSQSNY GPGKPDVKII PHPKTVVHED ARHVHKQVHL VKQVPVHRTR
     VQTIINEVPR IVTKPKKIKR TRIFRQYYPV DVPVIRRVTY LQPVHLERKV PVARMVVKDV
     PHHVVRTKKV DVPIDVPIKK IVEKKVVRYV ENKIFRPRPV VQEKVRVVHV PKPFPVDRVI
     VQKNPRPRII VEKKAVPVIR HIHTHKKQAV AVPRVKTVAE VVPNVVHQKV TYPVGKGGGS
     VQIPGGPLPV PEKF