ID   MQO1_PSEPK              Reviewed;         502 AA.
AC   Q88PU7;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Probable malate:quinone oxidoreductase 1 {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO 1 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] 1 {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo1 {ECO:0000255|HAMAP-Rule:MF_00212}; Synonyms=mqo-1;
GN   OrderedLocusNames=PP_0751;
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA   Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I.,
RA   Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A.,
RA   Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H.,
RA   Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C.,
RA   Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; AE015451; AAN66376.1; -; Genomic_DNA.
DR   RefSeq; NP_742912.1; NC_002947.4.
DR   RefSeq; WP_010951993.1; NC_002947.4.
DR   AlphaFoldDB; Q88PU7; -.
DR   STRING; 160488.PP_0751; -.
DR   EnsemblBacteria; AAN66376; AAN66376; PP_0751.
DR   KEGG; ppu:PP_0751; -.
DR   PATRIC; fig|160488.4.peg.805; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   PhylomeDB; Q88PU7; -.
DR   BioCyc; PPUT160488:G1G01-826-MON; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..502
FT                   /note="Probable malate:quinone oxidoreductase 1"
FT                   /id="PRO_0000128732"
SQ   SEQUENCE   502 AA;  54282 MW;  BCEA30DACCA736E3 CRC64;
     MAQNESVDVV LVGAGIMSAT LAVLLKELDP TLKLEVVEAM DSGAAESSNP WNNAGTGHAG
     LCELNYTPQA ADGSIDIKKA VHINTQFEVS RQFWAYLTKK GNFGSARAFI NPVPHLSYVE
     GDKGVSFLKK RFELLKQHHA FAEMEYTEDK AVMNDWMPLM MPGRPADQHI AATRVAKGTD
     VNFGALTNKL LKLLGDSPDA QVKYSKKVVG LRRNGSGWTV SIKDVNSGGS REVDARFVFL
     GAGGAALPLL QLSGIPESKG FGGFPVSGQW LRCDNPEIVK QHQAKVYSQA AVGAPPMSVP
     HLDTRVVDGK TSLLFGPYAG FTTKFLKHGS LMDLPLSVRM GNIGPMLAVA RDNMDLTKYL
     VSEVMQSMEQ RLEALRRFYP QAKAEDWRLE VAGQRVQIIK KDPKKGGVLQ FGTELVSAQD
     GSLAALLGAS PGASVTVSIM LELIERCFPE QAKGAWAAKL KEIFPAREKT LATDAALYHK
     ISADNDAALD LAESSPAAKH YA