ID   MQO3_PSEPK              Reviewed;         539 AA.
AC   Q88IS4;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Probable malate:quinone oxidoreductase 3 {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO 3 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] 3 {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo3 {ECO:0000255|HAMAP-Rule:MF_00212}; Synonyms=mqo-3;
GN   OrderedLocusNames=PP_2925;
OS   Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950
OS   / KT2440).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=160488;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440;
RX   PubMed=12534463; DOI=10.1046/j.1462-2920.2002.00366.x;
RA   Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA   Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA   Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA   Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I.,
RA   Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A.,
RA   Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H.,
RA   Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C.,
RA   Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
RT   "Complete genome sequence and comparative analysis of the metabolically
RT   versatile Pseudomonas putida KT2440.";
RL   Environ. Microbiol. 4:799-808(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; AE015451; AAN68533.1; -; Genomic_DNA.
DR   RefSeq; NP_745069.1; NC_002947.4.
DR   RefSeq; WP_010953827.1; NC_002947.4.
DR   AlphaFoldDB; Q88IS4; -.
DR   STRING; 160488.PP_2925; -.
DR   EnsemblBacteria; AAN68533; AAN68533; PP_2925.
DR   KEGG; ppu:PP_2925; -.
DR   PATRIC; fig|160488.4.peg.3098; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RHMAKAY; -.
DR   PhylomeDB; Q88IS4; -.
DR   BioCyc; PPUT160488:G1G01-3103-MON; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000556; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..539
FT                   /note="Probable malate:quinone oxidoreductase 3"
FT                   /id="PRO_0000128734"
FT   REGION          516..539
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  59671 MW;  526AB47EF530CA77 CRC64;
     MKITIKPKLA MAGLALAIGM LNAQAAETRK VDVLLVGGGI MSSTLAVWLN ELEPGWSMEM
     VERLDKVAEE SSNGWNNAGT GHSALAELNY TPEKDGKIDI SKAVEINESF QVTRQFLAWQ
     VKQGVLKNPH SFINTTPHMS FVWGDDNIRF LKKRYEALQA SPLFKPMQYS EDHEQIRKWV
     PLMMEGRDPN QKLAVTWTPI GTDVNFGEIT RQYVGYLQTR PNFDLKLSSE VQDITRNDDG
     SWHVEYKNLK NGSKAATDAR FLFIGAGGAA LPLLQKSGID EAKNYGGFPV GGSFLVTDNP
     AIAQRHMAKA YGIAATGAPP MSVPHLDTRV LDGKRLILFG PFATFSTKFL KQGSLLDLLA
     STSVHNAWPM VRVGVREFDL VQYLIGQVLQ SDDDRFEALR TYFPEAKKED WRLWQAGQRV
     QIIKKDEALG GVLKLGTEVV TSRDGSIAGL LGASPGASTA APIMLDVLNK VFKNKVASPE
     WQAKIKQIIP SYGIRLNDHP DQLEKEWAYT NEVLQLEPPV SPQRPESIRP ADSQGVASR