ID   MQO_ACTP2               Reviewed;         491 AA.
AC   A3N262;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=APL_1414;
OS   Actinobacillus pleuropneumoniae serotype 5b (strain L20).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=416269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L20;
RX   PubMed=18065534; DOI=10.1128/jb.01845-07;
RA   Foote S.J., Bosse J.T., Bouevitch A.B., Langford P.R., Young N.M.,
RA   Nash J.H.E.;
RT   "The complete genome sequence of Actinobacillus pleuropneumoniae L20
RT   (serotype 5b).";
RL   J. Bacteriol. 190:1495-1496(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000569; ABN74498.1; -; Genomic_DNA.
DR   RefSeq; WP_009875515.1; NC_009053.1.
DR   AlphaFoldDB; A3N262; -.
DR   STRING; 416269.APL_1414; -.
DR   EnsemblBacteria; ABN74498; ABN74498; APL_1414.
DR   KEGG; apl:APL_1414; -.
DR   PATRIC; fig|416269.6.peg.1473; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001432; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..491
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325484"
SQ   SEQUENCE   491 AA;  54074 MW;  CB55915CE9BDA023 CRC64;
     MQDSSSALES YSDVTLIGAG IMSGTLGAFL TELAPEKSLA IFEKLSAVGL ESSNEWNNAG
     TGHSALCELN YTEQKANGEV SVERAVKICE DFQLSLQLWS YLVETGRIQA PREFIHRIPH
     ISFVQGEQNA QFLQKRYQSL AQSHLFEGMQ FSRDHQQLAQ WMPLMMQNRD SNETLAASYI
     QYGTDVNFGE LTRKLFDYLV KQKAELNLNH TVKNIQRLAN GEWKLTVVDQ QGQKRVHRSK
     FVFIGGGGGA LPLLQKSGIT DGKNVGGFPV SGLFMVCNNP EVIAKHNAKV YGKAKLGAPP
     MSVPHLDTRF IEGKQSLLFG PFAGFTLKFL KQGSVLDLPT SVTPTNFCSV TKAGIKNLPL
     AHYLMKQAML TKAQRMADLR EFVPDAKDED WDVVVAGQRV QVIKGGEMRF GTEVIRAEDG
     SLAALLGASP GASTSVKAML DVLVSCFAAE LPQWQAKLTQ MLPSYGKALR NEPQLYAQIK
     QRVDQVLALA N