ID   MQO_ACTP7               Reviewed;         491 AA.
AC   B3H2E6;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=APP7_1519;
OS   Actinobacillus pleuropneumoniae serotype 7 (strain AP76).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Actinobacillus.
OX   NCBI_TaxID=537457;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AP76;
RA   Linke B., Buettner F., Martinez-Arias R., Goesmann A., Baltes N.,
RA   Tegetmeyer H., Singh M., Gerlach G.F.;
RT   "Genome and proteome analysis of A. pleuropneumoniae serotype 7.";
RL   Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP001091; ACE62171.1; -; Genomic_DNA.
DR   RefSeq; WP_005602054.1; NC_010939.1.
DR   AlphaFoldDB; B3H2E6; -.
DR   EnsemblBacteria; ACE62171; ACE62171; APP7_1519.
DR   KEGG; apa:APP7_1519; -.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   BioCyc; APLE537457:APP7_RS07820-MON; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001226; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..491
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000099866"
SQ   SEQUENCE   491 AA;  54075 MW;  48A0BA8B61750E27 CRC64;
     MQDSSSALES YSDVTLIGAG IMSGTLGAFL TELAPEKSLA IFEKLSAVGL ESSNEWNNAG
     TGHSALCELN YTEQKADGEV SVERAVKICE DFQLSLQLWS YLVETGRIQA PREFIHRIPH
     ISFVQGEQNA QFLQKRYQSL AQSHLFEGMQ FSRDHQQLAQ WMPLMMQNRD SNETLAASYI
     QYGTDVNFGE LTRKLFDYLV KQKAELNLNH TVKNIQRLAN GEWKLTVVDQ QGQKRVHRSK
     FVFIGGGGGA LPLLQKSGIT DGKNVGGFPV SGLFMVCNNP EVIAKHNAKV YGKAKLGAPP
     MSVPHLDTRF IEGKQSLLFG PFAGFTLKFL KQGSVLDLPT SVTPTNFCSV TKAGIKNLPL
     AHYLMKQAML TKAQRMADLR EFVPDAKDED WDVVVAGQRV QVIKGGEMRF GTEVIRAEDG
     SLAALLGASP GASTSVKAML DVLVSCFAAE LPQWQAKLTQ MLPSYGKALR NEPQLYAQIK
     QRVDQVLALA N