MQO_AZOC5
ID MQO_AZOC5 Reviewed; 500 AA.
AC A8I2M2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=AZC_1899;
OS Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG
OS 6465 / NBRC 14845 / NCIMB 13405 / ORS 571).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Azorhizobium.
OX NCBI_TaxID=438753;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB
RC 13405 / ORS 571;
RA Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T.,
RA Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B.,
RA Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.;
RT "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium
RT caulinodans ORS571.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; AP009384; BAF87897.1; -; Genomic_DNA.
DR RefSeq; WP_012170427.1; NC_009937.1.
DR AlphaFoldDB; A8I2M2; -.
DR STRING; 438753.AZC_1899; -.
DR EnsemblBacteria; BAF87897; BAF87897; AZC_1899.
DR KEGG; azc:AZC_1899; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_5; -.
DR OMA; RCDNPEV; -.
DR OrthoDB; 1371190at2; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000000270; Chromosome.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.50.50.60; -; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW Tricarboxylic acid cycle.
FT CHAIN 1..500
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_1000071747"
SQ SEQUENCE 500 AA; 53645 MW; 0B2ABC3849EEA6D2 CRC64;
MTFSQKTDTD VLLIGAGIMS ATLGTLLHAL EPSLRLTMLE RLDDCGLESS MGWNNAGTGH
AANCELNYTP QRADGSVDIS KALQVNTQFD ISRELWSHLV TTGAIPDPRA FLHPCPHMSF
VWGEENVAFL KARHAAMAAH HCYHGMDYSE DPAQIAQWAP LVMEGRDPAQ KIAATRIITG
TDVDYGALTH LLVGHLKTAG LDLRYNSEVI AIDRGDDGIW TVTFEDTVDG TRQQITAGFV
FIGAGGAAIE LLQKSGIPEA KGYAGFPVSG IWLRCDVDAV AARHHAKVYG KAASGSPPMS
VPHLDTRVIG GKTSLLFGPY AGFSTKFLKR GSLTDLFGSI TASNILPLLD VAKDNAALEE
YLIGQVFQSR HHQFEMLRQF FPQARRADWQ EAVAGQRVQI IKPDQGDPGG QLEFGTELVA
ASDKSLVALL GASPGASTAA AIAVHVLQTC FADRLTEDGW LPALRGALPS YGIDLITDAE
ACSASRKATA KVLKIDNIDA
