ID   MQO_BLOPB               Reviewed;         515 AA.
AC   Q492E3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=BPEN_548;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BPEN;
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000016; AAZ41158.1; -; Genomic_DNA.
DR   RefSeq; WP_011283069.1; NC_007292.1.
DR   AlphaFoldDB; Q492E3; -.
DR   STRING; 291272.BPEN_548; -.
DR   EnsemblBacteria; AAZ41158; AAZ41158; BPEN_548.
DR   KEGG; bpn:BPEN_548; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; VEINYNH; -.
DR   BioCyc; CBLO291272:BPEN_RS02705-MON; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000007794; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..515
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325487"
SQ   SEQUENCE   515 AA;  58085 MW;  0A3FD48D065944E1 CRC64;
     MSNVAVINQQ HRLIKITSSA DIVLIGAGIM SATFGMFLTI LEPTWRIHIY ERLSQPAQES
     SNVWNNAGTG HAAFCELNYT QYNNKNCSVD ISKAIAVNEA FEISRQFWAY LVEIKVLKYP
     SSFINNVPHM SFVWGEENVC FLKKRFQALL NSVLFSGMVY SEDLQQIRQW TPLIIDGRNV
     SQKIAATRME MGTDVNFGAL TQQLLNELKK NVNFKMYLQH DVVSVQNNND ATWDVHVIDR
     RCKHKKCIRT NYVFIGAGGR SLNLLQTSGI PEVYGYAGFP VGGQFLVTKN PKIVEQHLAK
     VYGKASVNAP PMSVPHIDTR ILNGEKILLF GPFATFSSKF LKYGSWLDLF HSLNKHNVIP
     ILQAGIDNFD LIKYLISQLV MSNMNRIDEL REYYPTVNPS DWTLVTAGQR VQIIKRNSNR
     RGILQFGTEV VNSGDGTLSA LLGASPGAST VVSIILQLLN TMFNNKINSD VWKNKLIDMI
     PSYTKNLNGD LILVNKIRQY TCNALKLNYI EAIDR