MQO_BORA1
ID MQO_BORA1 Reviewed; 500 AA.
AC Q2KX12;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 07-MAR-2006, sequence version 1.
DT 25-MAY-2022, entry version 85.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=BAV0729;
OS Bordetella avium (strain 197N).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=360910;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=197N;
RX PubMed=16885469; DOI=10.1128/jb.01927-05;
RA Sebaihia M., Preston A., Maskell D.J., Kuzmiak H., Connell T.D., King N.D.,
RA Orndorff P.E., Miyamoto D.M., Thomson N.R., Harris D., Goble A., Lord A.,
RA Murphy L., Quail M.A., Rutter S., Squares R., Squares S., Woodward J.,
RA Parkhill J., Temple L.M.;
RT "Comparison of the genome sequence of the poultry pathogen Bordetella avium
RT with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals
RT extensive diversity in surface structures associated with host
RT interaction.";
RL J. Bacteriol. 188:6002-6015(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; AM167904; CAJ48342.1; -; Genomic_DNA.
DR RefSeq; WP_012416425.1; NC_010645.1.
DR AlphaFoldDB; Q2KX12; -.
DR SMR; Q2KX12; -.
DR STRING; 360910.BAV0729; -.
DR EnsemblBacteria; CAJ48342; CAJ48342; BAV0729.
DR GeneID; 41392637; -.
DR KEGG; bav:BAV0729; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_4; -.
DR OMA; RCDNPEV; -.
DR OrthoDB; 1371190at2; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000001977; Chromosome.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.50.50.60; -; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW Tricarboxylic acid cycle.
FT CHAIN 1..500
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_0000325488"
SQ SEQUENCE 500 AA; 54850 MW; 938733533BC458FF CRC64;
MTTTSNLPEQ ADIVMIGAGI MSATLATVLK ALEPSLKIVM LETLNDCAME SSNGWNNAGT
GHAANCEMNY TPPRPDGTVD ISRALEVNTE FDLSRQLWSY LVKTGAIPDP QAFIHPCPHM
SMVWGADNVK YLRQRFKEMS AHHCYRGMEY SEDPKQIAEW VPLVMQGRSG NEPIAVTRIV
SGADVDYGAL THLLIKSLTE QAGFEVHYLK HVHDLARQRD GSWRIGIRDR GSKAQQTIQA
KFVFVGAGGG AIELLQKSGI PEGHGYGGFP VSGIWLRCDV DSMSERHHAK VYGKAPHGSP
PMSVPHLDTR IIGGKRSLLF GPYAGFSSRF LKHGSLTDLF RSVRPGNVLP MLDVAKDNWP
LTEYLVSQVL QSAGHQFEML RQYYPEARNH DWTHAVAGQR VQIIKPGTDK VGVLEFGTEL
VTSADRSFAA LLGASPGAST AAFIALEVLQ KCFADKLTAD AWLPRLKTVI PTYGVDLKTD
AEACFSIRKS TASVLNLDYV
