ID   MQO_BRADU               Reviewed;         512 AA.
AC   Q89XM4;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=bll0284;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000040; BAC45549.1; -; Genomic_DNA.
DR   RefSeq; NP_766924.1; NC_004463.1.
DR   RefSeq; WP_011083116.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89XM4; -.
DR   STRING; 224911.27348531; -.
DR   EnsemblBacteria; BAC45549; BAC45549; BAC45549.
DR   GeneID; 64020144; -.
DR   KEGG; bja:bll0284; -.
DR   PATRIC; fig|224911.44.peg.8804; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_5; -.
DR   InParanoid; Q89XM4; -.
DR   OMA; RCDNPEV; -.
DR   PhylomeDB; Q89XM4; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..512
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000128707"
SQ   SEQUENCE   512 AA;  55455 MW;  5B0FF5455898F765 CRC64;
     MPAASDRETD VVLIGAGIMS ATLGAFLKEL EPSLTIQMLE TLDDCAQESS DSWNNAGTGH
     AANCEMNYTP QRPDGSIDIS KALQVNVEFD LSRQFWSYLI GRGAIADPRS FIHPVPHMSF
     VHGTENVEFL RKRFKAMSAH HCYEGMEHTE DPRKIAEWAP LVMDGRSGDE PVAATRIITG
     TDVDYGALTH LLVGHLVSQP GCAVHYNSCV TGLVREQGGR WRIEVRDTAS GETRSVRAKF
     VFIGAGGGAL PLLEKSGLPE ARGYGGFPVS GIWLRCDDPE INKRHHAKVY GKAAVGSPPM
     SVPHLDTRVI GGKHSLLFGP YAGFSSKFLK HGSLLDLFES IRPANVKPLL SVARDNFDLT
     EYLVGQVLQS ESHRLAALDE YFPKADPKDW RLQVAGQRVQ IIKPDVKRGG LLEFGTELVG
     ADDHSLVALL GASPGASTAA FIAISVLEKC FAGELTASAW LPKLKQIVPS YGVSLIDDAD
     FCRQIRATTA EVLKVDNIPQ PAARAPAAAK RA