ID   MQO_BREBN               Reviewed;         499 AA.
AC   C0Z9W8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=BBR47_58450;
OS   Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=358681;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=47 / JCM 6285 / NBRC 100599;
RA   Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W.,
RA   Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S.,
RA   Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H.,
RA   Udaka S., Tanikawa S., Fujita N.;
RT   "Brevibacillus brevis strain 47, complete genome.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP008955; BAH46822.1; -; Genomic_DNA.
DR   RefSeq; WP_015894006.1; NC_012491.1.
DR   AlphaFoldDB; C0Z9W8; -.
DR   STRING; 358681.BBR47_58450; -.
DR   EnsemblBacteria; BAH46822; BAH46822; BBR47_58450.
DR   KEGG; bbe:BBR47_58450; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_9; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001877; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..499
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000124766"
SQ   SEQUENCE   499 AA;  54991 MW;  6642BA8BC5BEBF10 CRC64;
     MSSIQQKTDV ILIGAGVMSA TLGALLKELA PELEIKVFEK LAKAGEESSN EWNNAGTGHA
     ALCELNYTSE KADGSIDISK AIKINEHFQL SRQFWAYLVK NNLIQNPQDF IMPIPHMSMV
     QGEKNVSFLK KRFEALANNP LFQGMEYSDD PEKLKEWIPL IMEGRATNEP IAATKIDSGT
     DVNFGALTRM LFDYLKTKDV AINYKHAVED IKRTSDGMWK LKVYNMGTGN IEEHIAKFVF
     IGGGGGSLHL LQKTGIPESK HIGGFPVSGL FMVCKNQEVV EQHHAKVYGK AKVGAPPMSV
     PHLDTRYIDN KKSLLFGPFA GFSPKFLKTG SNLDLITSVK PNNVITMLAA GVKEMALTKY
     LIEQVMLSHE KRMEELREFI PNAKSEDWGI VVAGQRVQVI KDTPAGKGTL QFGTEVVSAA
     DGSVAALLGA SPGASTAVQV MLEVLEKCFP QRMAEWEPKI KEMIPSYGVS LMQNQELLHE
     IQRSTDEALG LSEKELAYS