MQO_CHRSD
ID MQO_CHRSD Reviewed; 508 AA.
AC Q1QUD2;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=Csal_2579;
OS Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 /
OS NCIMB 13768 / 1H11).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Chromohalobacter.
OX NCBI_TaxID=290398;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11;
RX PubMed=22675587; DOI=10.4056/sigs.2285059;
RA Copeland A., O'Connor K., Lucas S., Lapidus A., Berry K.W., Detter J.C.,
RA Del Rio T.G., Hammon N., Dalin E., Tice H., Pitluck S., Bruce D.,
RA Goodwin L., Han C., Tapia R., Saunders E., Schmutz J., Brettin T.,
RA Larimer F., Land M., Hauser L., Vargas C., Nieto J.J., Kyrpides N.C.,
RA Ivanova N., Goker M., Klenk H.P., Csonka L.N., Woyke T.;
RT "Complete genome sequence of the halophilic and highly halotolerant
RT Chromohalobacter salexigens type strain (1H11(T)).";
RL Stand. Genomic Sci. 5:379-388(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; CP000285; ABE59926.1; -; Genomic_DNA.
DR AlphaFoldDB; Q1QUD2; -.
DR STRING; 290398.Csal_2579; -.
DR EnsemblBacteria; ABE59926; ABE59926; Csal_2579.
DR KEGG; csa:Csal_2579; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_6; -.
DR OMA; RCDNPEV; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000000239; Chromosome.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.50.50.60; -; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW Tricarboxylic acid cycle.
FT CHAIN 1..508
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_1000023794"
SQ SEQUENCE 508 AA; 55933 MW; 2EA022A8F22EBD36 CRC64;
MVGTHMDESV DIVLVGAGVM SATLATLLHE LEPDARIEII ERLDSTASES SFAWNNAGTG
HAGLCELNYT PRADDGSISL DKAIHTNTLF EESKQFWSYL VEKGNLGDPG RFVHPVPHMS
FVRGEDDVRF LRDRYHAMRE HPCFEGMEYT EDRSVIGQWA PLLLDGREGD EPLAATRVAT
GTDVDFGALT RQLLARLEEK PDEQVRITTG QTVEDLTRNE DGSWRIKIAG NDDTQRTLNA
RFVFLGAGGA SLHLLQKSGI PEGKGYAGFP VSGQWLRCDK PEIVSRHNAK VYSKAPIGAP
PMSVPHLDTR NVDGSPSLLF GPFAGFTTKF LKTGSVMDLA KSVRSSNLSP MLSVARDNFS
LVKYLIDQVR LSHEQRVDEL RTFYPMAKND DWRLEVAGQR VQVIKKDPQK GGILQFGTEV
VAASDGSLAA LLGASPGAST ATSIMLNLVE QCFPEKFASQ AWQQRLHDLV PARAETLADN
GDLLRDVRRR THDTLKLVDT QPSPEPVT
