ID   MQO_CITK8               Reviewed;         553 AA.
AC   A8AE07;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=CKO_00565;
OS   Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Citrobacter.
OX   NCBI_TaxID=290338;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-895 / CDC 4225-83 / SGSC4696;
RG   The Citrobacter koseri Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Latreille P., Courtney L., Wang C., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000822; ABV11720.1; -; Genomic_DNA.
DR   RefSeq; WP_012131544.1; NC_009792.1.
DR   AlphaFoldDB; A8AE07; -.
DR   STRING; 290338.CKO_00565; -.
DR   EnsemblBacteria; ABV11720; ABV11720; CKO_00565.
DR   GeneID; 45134801; -.
DR   KEGG; cko:CKO_00565; -.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000008148; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..553
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000023795"
FT   REGION          534..553
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   553 AA;  60874 MW;  F7CB5E240CA2D896 CRC64;
     MKKVTAMLFT MAVGLNAVSM AAKAKATEEQ ETDVLLIGGG IMSATLGTYL QELEPEWSMT
     MVERLDGVAQ ESSNGWNNAG TGHSALMELN YTPKKADGSV SIEKAVDINE AFQVSRQFWA
     HQVQSGVLHE PHSFINTVPH MSFVWGDDNV NFLRARYTAL QQSTLFRGMR YSEDHAQIKE
     WAPLVMEGRD PKQKVAATRT EIGTDVNYGE ITRQLVASLQ KKPNFALQLN TEVRGFKRNA
     DNSWTVTVAD LKNGEAEHAI KAKFVFIGAG GAALKLLQET GIPEAKDYAG FPVGGQFLVS
     ENPDVVNNHL AKVYGQASVG APPMSVPHID TRILDGKRVV LFGPFATFST KFLKNGSLWD
     LLSSTTTSNF MPMVNVGMDN FDLVKYLISQ VMLSDDERFE ALKEYYPQAK KEDWRLWQAG
     QRVQIIKRDE DKGGVLRLGT EVVSDKDGTI AALLGASPGA STAAPIMLHL MEKVFKEKVA
     SPEWQAKLKT IVPSYGTKLN GNIEATEQEL QYTSDVLGLK YDKPQVVDEA PKPQLKPQVQ
     PQPAHKAVAD IAL