MQO_CLAM3
ID MQO_CLAM3 Reviewed; 492 AA.
AC A5CPE3;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=CMM_0904;
OS Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382).
OC Bacteria; Actinobacteria; Micrococcales; Microbacteriaceae; Clavibacter.
OX NCBI_TaxID=443906;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 382;
RX PubMed=18192381; DOI=10.1128/jb.01595-07;
RA Gartemann K.-H., Abt B., Bekel T., Burger A., Engemann J., Fluegel M.,
RA Gaigalat L., Goesmann A., Graefen I., Kalinowski J., Kaup O., Kirchner O.,
RA Krause L., Linke B., McHardy A., Meyer F., Pohle S., Rueckert C.,
RA Schneiker S., Zellermann E.-M., Puehler A., Eichenlaub R., Kaiser O.,
RA Bartels D.;
RT "The genome sequence of the tomato-pathogenic actinomycete Clavibacter
RT michiganensis subsp. michiganensis NCPPB382 reveals a large island involved
RT in pathogenicity.";
RL J. Bacteriol. 190:2138-2149(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; AM711867; CAN00941.1; -; Genomic_DNA.
DR AlphaFoldDB; A5CPE3; -.
DR SMR; A5CPE3; -.
DR STRING; 443906.CMM_0904; -.
DR EnsemblBacteria; CAN00941; CAN00941; CMM_0904.
DR KEGG; cmi:CMM_0904; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_11; -.
DR OMA; PHLDTRW; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000001564; Chromosome.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.50.50.60; -; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT CHAIN 1..492
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_0000325492"
SQ SEQUENCE 492 AA; 53864 MW; C67007DAA5459171 CRC64;
MSESAEPVDV VLVGGGIMSA TLGTLIKQLE PDWTIQIFER LGEVAMESSN PWNNAGTGHA
ALCELNYTPE KDGKIEIGSA TRINEQFQLS RQFWAHLVTA GAVPEPKEFI NPTPHMTFVR
GKENAEFLRR RFDAMRAHPL FEAMEYSEDP AVIHSWAPLL VLQREKDEVI AATRFEGGTD
VDFGALTNKL IDYLTEHGAA LHLNHEVRGL SQNPDGSWHL RIRNDVGRST VQVDAKFVFI
GAGGGALPLL QKSGIPEIKG FGGFPISGEW FRTDDPEIVA RHRAKVYGKA AIGSPPMSVP
HLDTRVVGGE TSLLFGPYAG FSPRFLKKGS LLDLFASIRP HNIIPMLAVA KDNLSLIKYL
VSQLIASKEK KFDALREFMP TADPKDWYQV TAGQRVQVMK KDAKKGGVLQ FGTEVVAAAD
GSIAGLLGAS PGASTAVPIM LDVLERCFPD RIAGWKKPLT RMIPNYGTLV ASDPKKTPKI
IQETAEVLEL QH
