MQO_CORA7
ID MQO_CORA7 Reviewed; 500 AA.
AC C3PH30;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=cauri_1541;
OS Corynebacterium aurimucosum (strain ATCC 700975 / DSM 44827 / CIP 107346 /
OS CN-1) (Corynebacterium nigricans).
OC Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC Corynebacterium.
OX NCBI_TaxID=548476;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700975 / DSM 44827 / CIP 107346 / CN-1;
RX PubMed=20137072; DOI=10.1186/1471-2164-11-91;
RA Trost E., Gotker S., Schneider J., Schneiker-Bekel S., Szczepanowski R.,
RA Tilker A., Viehoever P., Arnold W., Bekel T., Blom J., Gartemann K.H.,
RA Linke B., Goesmann A., Puhler A., Shukla S.K., Tauch A.;
RT "Complete genome sequence and lifestyle of black-pigmented Corynebacterium
RT aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a
RT vaginal swab of a woman with spontaneous abortion.";
RL BMC Genomics 11:91-91(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; CP001601; ACP33134.1; -; Genomic_DNA.
DR RefSeq; WP_010190354.1; NZ_ACLH01000084.1.
DR AlphaFoldDB; C3PH30; -.
DR STRING; 548476.cauri_1541; -.
DR EnsemblBacteria; ACP33134; ACP33134; cauri_1541.
DR GeneID; 31924171; -.
DR KEGG; car:cauri_1541; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_11; -.
DR OMA; PHLDTRW; -.
DR OrthoDB; 1371190at2; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000002077; Chromosome.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR Gene3D; 3.50.50.60; -; 1.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW Tricarboxylic acid cycle.
FT CHAIN 1..500
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_1000124767"
SQ SEQUENCE 500 AA; 55235 MW; 5CE595EC660F5119 CRC64;
MSSDKKTAQV VDEVEVALIG AGIMSATLGA MLRELEPSWT QMVFERLDGP ALESSSPWNN
AGTGHSALCE LNYTPEKNGR IDISKALNIN EKFQVSRQFW SHQLNNGILT DPKAFINPVP
HVSFAQGSIQ VDYLKRRFDA LKDNHMFPNM QFSDDDATFQ EKLPLMSQGR DFNSQKVAIS
WTDAGTDVNF GALAKQFFTA AKAAGTEIRY GHEVVDIKRE GSKWRVVAKN LHTGDYQAVH
AKFVFVGAGG YALDLLRKAG VREVSGFAGF PVSGLWLRSK NPELVKQHHA KVYGKAAVGA
PPMSVPHLDT RVIDGEEGLL FGPYGGWSPK FLKKGSYLDL FKSIRPDNIT SYLGVAAQEF
GLTKYLVTEV LKDFDKRVET LKEYVPSADP ADWETVIAGQ RVQVIKPAGA PQFGSLEFGT
TLINNPEGNI AGLLGASPGA SITPAIMIEL LERCFGENMI QWGDKIQEMI PSYGTKLSKD
KKLYNEMWEY TQKTLQLESK
