ID   MQO_CORJK               Reviewed;         490 AA.
AC   Q4JV42;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=jk1151;
OS   Corynebacterium jeikeium (strain K411).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=306537;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K411;
RX   PubMed=15968079; DOI=10.1128/jb.187.13.4671-4682.2005;
RA   Tauch A., Kaiser O., Hain T., Goesmann A., Weisshaar B., Albersmeier A.,
RA   Bekel T., Bischoff N., Brune I., Chakraborty T., Kalinowski J., Meyer F.,
RA   Rupp O., Schneiker S., Viehoever P., Puehler A.;
RT   "Complete genome sequence and analysis of the multiresistant nosocomial
RT   pathogen Corynebacterium jeikeium K411, a lipid-requiring bacterium of the
RT   human skin flora.";
RL   J. Bacteriol. 187:4671-4682(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CR931997; CAI37315.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q4JV42; -.
DR   SMR; Q4JV42; -.
DR   STRING; 306537.jk1151; -.
DR   EnsemblBacteria; CAI37315; CAI37315; jk1151.
DR   KEGG; cjk:jk1151; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_11; -.
DR   OMA; PHLDTRW; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000545; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..490
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000023797"
SQ   SEQUENCE   490 AA;  53914 MW;  5A8AB315A3CBEB74 CRC64;
     MAHKDSVDVA LIGAGVISTT LSVMLKQLQP DWSQVIIERL DTPGAESSDP WNNAGTGHSA
     LCELNYTPEV NGKIDISKAV GVNEKFQVSR QFWSYLVEQN VLGDPSEFIN KVPHVSFAQG
     MDQVDYLKAR YEALKDHPLF PNMQYSDSDE KFAEFLPLMA RGRDFNNPVA ISWFDEGTDI
     NYGALTRQYL DAVTAQGVEV RFGNEVKNIN RDGSKWKITT KNLHTGDTSM VTANFVFIGA
     GGMALPLLQK AGIPEIKGYG GFPVSGQWLR CTNPELVEQH QAKVYGKASV GAPPMSVPHL
     DTRVIDGKKG LLFGPYAGWT PKFLKKGSYL DLFKSLRVGN LPSYLGVGVQ EMGLTKYLIE
     EVLKDQAARV ESLREYMPEA RAEDWELVTA GQRVQVIKPI GAPKFGSLEF GTALINSNDG
     SIAGLMGASP GASIAPSAML EVLERCFGNR IADWAPKLRE MIPSYGTRLS KDANLFNEQW
     DRSQKALKLV