ID   MQO_CROS8               Reviewed;         552 AA.
AC   A7MNG1;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=ESA_03816;
OS   Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=290339;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-894;
RX   PubMed=20221447; DOI=10.1371/journal.pone.0009556;
RA   Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L.,
RA   Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A.,
RA   Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K.,
RA   McClelland M., Forsythe S.J.;
RT   "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic
RT   hybridization analysis with other Cronobacter species.";
RL   PLoS ONE 5:E9556-E9556(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000783; ABU79002.1; -; Genomic_DNA.
DR   RefSeq; WP_012126077.1; NC_009778.1.
DR   AlphaFoldDB; A7MNG1; -.
DR   EnsemblBacteria; ABU79002; ABU79002; ESA_03816.
DR   KEGG; esa:ESA_03816; -.
DR   PATRIC; fig|290339.8.peg.3390; -.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000260; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..552
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325494"
FT   REGION          530..552
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   552 AA;  60653 MW;  B7CEAD2327F6EAB8 CRC64;
     MSKITLSRKH APAFSLIALL VSSAAYAENT TEKTDVLLIG GGIMSASLGT VLQEIQPDWK
     QLMVEKLDGV ALESSNGWNN AGTGHSANME LNYTPEREDG SIDVTKALEI NEAFMISRQF
     WSSQVKRGVL NDPHSFINST PHMSFVWGDK NVEYLTKRYQ ALQQTTLFQG MQFSTDQQQI
     KKWAPLIIEG RDPKQKVAAT WTPVGTDVNY GEITRQLVGS LKKTSNFKLE TSSEVTDFKR
     NADNSWHVTI TDVKSGKEHA VDAKYVFIGA GGGALKLLQK TGIPEADNYA GFPVGGSFLV
     SENPEIARQH GEKVYGQASV GAPPMSVPHL DARFLDGKRV VLFGPFATFS TKFLKNGSFF
     DLLSTTTTSN FMPMTDVGLD NFDLVKYLIG QVMLSDEDRF EALKEYYPTA RKEDWKLIQA
     GQRVQIIKKD PEKGGVLKLG TEIVTDQQKT LAALLGASPG ASTAAPISIN VIKQLFPEQF
     KSEAWQSKLR EIVPSYGQKL NGNVALTQQV WDETAATLQL TKPPVIQMKD AKPATPEAKP
     AQASSPQHDM AL