ID   MQO_ENT38               Reviewed;         551 AA.
AC   A4WCM3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=Ent638_2788;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=638;
RX   PubMed=20485560; DOI=10.1371/journal.pgen.1000943;
RA   Taghavi S., van der Lelie D., Hoffman A., Zhang Y.B., Walla M.D.,
RA   Vangronsveld J., Newman L., Monchy S.;
RT   "Genome sequence of the plant growth promoting endophytic bacterium
RT   Enterobacter sp. 638.";
RL   PLoS Genet. 6:E1000943-E1000943(2010).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABP61453.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000653; ABP61453.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041689471.1; NC_009436.1.
DR   AlphaFoldDB; A4WCM3; -.
DR   STRING; 399742.Ent638_2788; -.
DR   EnsemblBacteria; ABP61453; ABP61453; Ent638_2788.
DR   KEGG; ent:Ent638_2788; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000230; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..551
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325495"
FT   REGION          525..551
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   551 AA;  60670 MW;  8FCB867FCC2F81BE CRC64;
     MKKMTAMLFS MAVGLNAVSM TAMADAPKEQ ETDVLLIGGG IMSATLGTYL QELQPDWSMT
     MVERLDGVAK ESSNGWNNAG TGHSALMELN YTPQKKDGSI SIEKAVEINE AFQVSRQFWS
     HQVNSGVMHD PHSFINTVPH MSFVWGDQNV NFLRARYAAL QQSSLFRGMK FSEDHAQIKE
     WAPLVMEGRD PNQKVAATRT EIGTDVNYGE ITHQLVASLQ KKDDFHLQLS TEVRGFKRNA
     DNSWSVTVAD LKNNEAEHVI KAKFVFIGAG GAALKLLQET GIPEADDYAG FPVGGQFLVS
     ENPEVVNRHL AKVYGQASVG APPMSVPHID TRMLDGKRVV LFGPFATFST KFLKNGSLWD
     LLSSTTTSNF MPMVDVGMDN FDLVKYLMSQ VMLSDDDRFA ALQEYYPQAK KEDWRLWQAG
     QRVQIIKRDP KEGGVLRLGT EVVSDKEGTI AALLGASPGA STAAPIMLHL MEKVFKDKVA
     SPEWQAKLKT IIPSYGTKLN GNVAATEQEL EFTSRVLQLK YEKPQTAAAA PQAQPQLKPQ
     PDAKPVADIA L