ID   MQO_EXISA               Reviewed;         499 AA.
AC   C4L056;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=EAT1b_1793;
OS   Exiguobacterium sp. (strain ATCC BAA-1283 / AT1b).
OC   Bacteria; Firmicutes; Bacilli; Bacillales;
OC   Bacillales Family XII. Incertae Sedis; Exiguobacterium;
OC   unclassified Exiguobacterium.
OX   NCBI_TaxID=360911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1283 / AT1b;
RX   PubMed=21460088; DOI=10.1128/jb.00303-11;
RA   Vishnivetskaya T.A., Lucas S., Copeland A., Lapidus A., Glavina del Rio T.,
RA   Dalin E., Tice H., Bruce D.C., Goodwin L.A., Pitluck S., Saunders E.,
RA   Brettin T., Detter C., Han C., Larimer F., Land M.L., Hauser L.J.,
RA   Kyrpides N.C., Ovchinnikova G., Kathariou S., Ramaley R.F., Rodrigues D.F.,
RA   Hendrix C., Richardson P., Tiedje J.M.;
RT   "Complete genome sequence of the Thermophilic Bacterium Exiguobacterium sp.
RT   AT1b.";
RL   J. Bacteriol. 193:2880-2881(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP001615; ACQ70719.1; -; Genomic_DNA.
DR   RefSeq; WP_015880278.1; NC_012673.1.
DR   AlphaFoldDB; C4L056; -.
DR   STRING; 360911.EAT1b_1793; -.
DR   EnsemblBacteria; ACQ70719; ACQ70719; EAT1b_1793.
DR   KEGG; eat:EAT1b_1793; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_9; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000716; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..499
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000204198"
SQ   SEQUENCE   499 AA;  54959 MW;  6E44169B7570690D CRC64;
     MSSTQTRTDV ILIGAGIMSA TLGSLFKELV PEWNIKVFEK LDAAGEESSN EWNNAGTGHA
     ALCELNYTTE NADGTIDISK AVNVNEQFQI SRQFWAHLVK QGLIENPGAF IRSIPHMSMV
     QGEKNVDFLK RRLEALTTNP LFEGMVLSDD PSQLQEWIPL IMDGRTSDEP IAATKIDSGT
     DVNFGALTRM LFDHLTSNGV ELNYGHSVED VKRLENGHWE VKVKDMSQNT IETHTAPFLF
     IGGGGGSLPL LQKTGIPESK QIGGFPVSGL FLVCKNREVI EQHHAKVYGK AKVGAPPMSV
     PHLDTRFIDG RKELLFGPFA GFTPKFLKTG SNLDLIRSVK PNNVITMLAA GAKEMPLTKY
     LIEQVLLSHD KRMDELREFI PNAKNEDWEI VVAGQRVQVI KDTPQGKGTL QFGTEVVSSE
     DGSVAALLGA SPGASTAVHV MLKVLEQCFP QHLPEWEPKI KEMVPSYGLK LSEHPDLFKT
     IHESTAITLG LEEKDMVHN