ID   MQO_FLAJ1               Reviewed;         497 AA.
AC   A5FGX2;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=Fjoh_2529;
OS   Flavobacterium johnsoniae (strain ATCC 17061 / DSM 2064 / JCM 8514 / NBRC
OS   14942 / NCIMB 11054 / UW101) (Cytophaga johnsonae).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=376686;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17061 / DSM 2064 / JCM 8514 / NBRC 14942 / NCIMB 11054 / UW101;
RX   PubMed=19717629; DOI=10.1128/aem.01495-09;
RA   McBride M.J., Xie G., Martens E.C., Lapidus A., Henrissat B., Rhodes R.G.,
RA   Goltsman E., Wang W., Xu J., Hunnicutt D.W., Staroscik A.M., Hoover T.R.,
RA   Cheng Y.Q., Stein J.L.;
RT   "Novel features of the polysaccharide-digesting gliding bacterium
RT   Flavobacterium johnsoniae as revealed by genome sequence analysis.";
RL   Appl. Environ. Microbiol. 75:6864-6875(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000685; ABQ05556.1; -; Genomic_DNA.
DR   RefSeq; WP_012024595.1; NZ_MUGZ01000022.1.
DR   AlphaFoldDB; A5FGX2; -.
DR   SMR; A5FGX2; -.
DR   STRING; 376686.Fjoh_2529; -.
DR   EnsemblBacteria; ABQ05556; ABQ05556; Fjoh_2529.
DR   KEGG; fjo:Fjoh_2529; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_10; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000006694; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..497
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000204199"
SQ   SEQUENCE   497 AA;  55293 MW;  1232893BDFB371EF CRC64;
     MPDNTIRSNS EVVLIGAGIM SATLGLILKE LQPDIKIEIY ERLDVAAAES SDAWNNAGTG
     HSAFCELNYT PEKADGSIDP KKAISIAESF EISRQFWSYL VQQNKVPSPE NFIKSVPHMS
     FVWGDKNVEY LRKRFEALQS NPIFADMTFS TDFNQLKEWM PLVMEGREAD EKLAATHMEI
     GTDVNFGALT RSMFNYLEKL DGVTLYFNHE VKKLKQREDK SWRIKITDLS TGQKRKAYTK
     FVFIGAGGGS LPLLEKADVP EGHGYGGFPV SGQWLKCTNP EVIAKHQAKV YGKASVGAPP
     MSVPHIDTRV IDGEKALLFG PFAGFSTRFL KNGSYLDLPL SIKANNLIPM LSAGFHNIPL
     TKYLIEQVRQ SPKDRMKALR EYLPTARSKD WKLEKAGQRV QVIKKGKDGG GVLEFGTEVI
     NTHDGTLAVL LGASPGASTA VAIMVDLISR CFTNQIKTPE WEAKMKEMIP SYGKTLNDKP
     ELLAEMRKHT AEVLKIK