ID   MQO_FLAPJ               Reviewed;         496 AA.
AC   A6H0E6;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=FP1752;
OS   Flavobacterium psychrophilum (strain ATCC 49511 / DSM 21280 / CIP 103535 /
OS   JIP02/86).
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=402612;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49511 / DSM 21280 / CIP 103535 / JIP02/86;
RX   PubMed=17592475; DOI=10.1038/nbt1313;
RA   Duchaud E., Boussaha M., Loux V., Bernardet J.-F., Michel C., Kerouault B.,
RA   Mondot S., Nicolas P., Bossy R., Caron C., Bessieres P., Gibrat J.-F.,
RA   Claverol S., Dumetz F., Le Henaff M., Benmansour A.;
RT   "Complete genome sequence of the fish pathogen Flavobacterium
RT   psychrophilum.";
RL   Nat. Biotechnol. 25:763-769(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; AM398681; CAL43819.1; -; Genomic_DNA.
DR   RefSeq; WP_011963862.1; NC_009613.3.
DR   RefSeq; YP_001296626.1; NC_009613.3.
DR   AlphaFoldDB; A6H0E6; -.
DR   STRING; 402612.FP1752; -.
DR   EnsemblBacteria; CAL43819; CAL43819; FP1752.
DR   GeneID; 66552061; -.
DR   KEGG; fps:FP1752; -.
DR   PATRIC; fig|402612.5.peg.1771; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_10; -.
DR   OMA; PHLDTRW; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000006394; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..496
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325497"
SQ   SEQUENCE   496 AA;  55264 MW;  A958517280D79F00 CRC64;
     MARQKIESDI VLIGAGIMSA TLGLLLKELN PKLKIEIFER LDIAAAESSD AWNNAGTGHA
     AFCELNYTPE LEDGTIETKK ALKISEAFEV SRQLWTYLVE KGLLQNPENF IKSVPHMSLV
     WGNDNVEYLR KRFEALQQFH LFKTMEFSDN IEKIKEWAPL VMENRNSKDK IAATSMKLGT
     DVNFGTLTRN MFKYLETLEG VTMHFNHDVY GLKKREDGRW RAKVKNIATG EKKKIFAPFV
     FIGAGGGSLL LLEKANIPEG QGFGGFPVSG QWLKCTNPEV IQKHSAKVYG KASVGAPPMS
     VPHIDTRMID GKKALLFGPY AGFSTKFLKN GSYFDLIKSI EFSNIKPMLG AGVKNIPLTK
     YLIEQVIQSS DDRLKALKEY VPSAKKEDWV LENAGQRVQV IKKDKDGHGI LEFGTEVVTA
     HDGSLAVLLG ASPGASTAVQ IMVDLITKCF PEEVKTTIWQ NKLKEMIPSY GQSLNENTVL
     CDQIRAKTNE ILKLKV