ID   MQO_GLUOX               Reviewed;         500 AA.
AC   Q5FP90;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=GOX2070;
OS   Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Gluconobacter.
OX   NCBI_TaxID=290633;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=621H;
RX   PubMed=15665824; DOI=10.1038/nbt1062;
RA   Prust C., Hoffmeister M., Liesegang H., Wiezer A., Fricke W.F.,
RA   Ehrenreich A., Gottschalk G., Deppenmeier U.;
RT   "Complete genome sequence of the acetic acid bacterium Gluconobacter
RT   oxydans.";
RL   Nat. Biotechnol. 23:195-200(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000009; AAW61806.1; -; Genomic_DNA.
DR   RefSeq; WP_011253583.1; NZ_LT900338.1.
DR   AlphaFoldDB; Q5FP90; -.
DR   STRING; 290633.GOX2070; -.
DR   EnsemblBacteria; AAW61806; AAW61806; GOX2070.
DR   KEGG; gox:GOX2070; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_5; -.
DR   OMA; RCDNPEV; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000006375; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..500
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000023803"
SQ   SEQUENCE   500 AA;  54100 MW;  2606F40BFFB27467 CRC64;
     MPSLSSLCPD IVLIGAGIMS STLAALLREL DPSLSMVMFE TLSDCGQESS YAWNNAGTGH
     AGNCELNYTP QRADGSVDIS KALAVNTEFD LSRQLWAHWV REGRIADPAA FVQPCPHISL
     VWGAENVAFL KARYEAMVAH HCFADMEYTD DPAVIAQWAP LAMAGRDTTQ PVAATRIREG
     TDVNFGALTH ALTASLKTDR SVSIHYNHRV TDLTRTEDGR WRVTATDTES GHAITVLTRF
     VFIGAGGNAL PLLQKSGIPE ATHYAGFPVS GLWLRCTDPA ITRQHHAKVY GKAPVGSPPM
     SVPHLDTRVI DGKSCLLFGP YAGFSTKFLK SGSWTDYFRS LTPKNIIPAL TAGKDNLGLL
     DYLVKQVIQT NEARFQALLD FYPTARPEDW SKVVAGQRVQ IIRPDSGLHG KLRFGTELVK
     NADRSLVAVL GASPGASIAA SVALQVVQGC FPERLVEGDW LPRLRQVFPA YGVDLTQDAA
     ACATLRRDTA QVLGIASEAG