ID   MQO_GRABC               Reviewed;         498 AA.
AC   Q0BTB0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212};
GN   OrderedLocusNames=GbCGDNIH1_1044;
OS   Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Granulibacter.
OX   NCBI_TaxID=391165;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1260 / CGDNIH1;
RX   PubMed=17827295; DOI=10.1128/jb.00793-07;
RA   Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E.,
RA   Kupko J.J. III, Barbian K.D., Babar A., Dorward D.W., Holland S.M.;
RT   "Genome sequence analysis of the emerging human pathogenic acetic acid
RT   bacterium Granulibacter bethesdensis.";
RL   J. Bacteriol. 189:8727-8736(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000394; ABI61942.1; -; Genomic_DNA.
DR   RefSeq; WP_011631751.1; NC_008343.2.
DR   AlphaFoldDB; Q0BTB0; -.
DR   STRING; 391165.GbCGDNIH1_1044; -.
DR   EnsemblBacteria; ABI61942; ABI61942; GbCGDNIH1_1044.
DR   KEGG; gbe:GbCGDNIH1_1044; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_5; -.
DR   OMA; RCDNPEV; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001963; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..498
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000023804"
SQ   SEQUENCE   498 AA;  54230 MW;  BDF86DB8CE0FAEEE CRC64;
     MTSSANLRPD IVLIGAGIMG ATFGTLLKEL NPSYSMMMFE RLSDCGQESS QSWNNAGTGH
     AANCELNYTP QRPDGTVEIT QALRVNTEFD LSRQLWSYLV TKGAIPDPQS FIHPCPHMSM
     VWGAENVAFL KARFQAMSAH HCYHGMEYTE DGAQIEKWAP LTMEGRDPAE PVAATRIITG
     TDVDYGSLTH LLVAHLKAQP DFDLHYNTEV EGLDREPDGR WRVTFKDVNS GERHSVSAGF
     VFIGAGGASI DLLQKSNIPE GKGYGGFPVS GIWLRCDVDA VTQRHHAKVY GKASSGSPPM
     SVPHLDTRVI DGKTSLLFGP YAGFSTKFLK HGSLTDLFGS ITLHNIGPLL DVGRHNIELT
     EYLIAQVLQT HHHQFEMLKA FFPNAKRADW KEAVAGQRVQ VIKPYPDGGG FLEFGTEIVP
     AADHSLVALL GASPGASTAA AIALEVLEAC FADRLTDDAW LPALKRIIPT YGIDLREDAE
     ACRASRAATA SVLNIDNI