ID   MQO_HAHCH               Reviewed;         497 AA.
AC   Q2SF51;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=HCH_04006;
OS   Hahella chejuensis (strain KCTC 2396).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae; Hahella.
OX   NCBI_TaxID=349521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KCTC 2396;
RX   PubMed=16352867; DOI=10.1093/nar/gki1016;
RA   Jeong H., Yim J.H., Lee C., Choi S.-H., Park Y.K., Yoon S.H., Hur C.-G.,
RA   Kang H.-Y., Kim D., Lee H.H., Park K.H., Park S.-H., Park H.-S., Lee H.K.,
RA   Oh T.K., Kim J.F.;
RT   "Genomic blueprint of Hahella chejuensis, a marine microbe producing an
RT   algicidal agent.";
RL   Nucleic Acids Res. 33:7066-7073(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000155; ABC30723.1; -; Genomic_DNA.
DR   RefSeq; WP_011397790.1; NC_007645.1.
DR   AlphaFoldDB; Q2SF51; -.
DR   STRING; 349521.HCH_04006; -.
DR   EnsemblBacteria; ABC30723; ABC30723; HCH_04006.
DR   KEGG; hch:HCH_04006; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000238; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..497
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325498"
SQ   SEQUENCE   497 AA;  54587 MW;  FAD4E8D22F3C6A21 CRC64;
     MTVKKADVLL VGGGVMSTTL GTMLMQLDPS LNIVMVERLD HVAHESTYGW NNAGTGHAGY
     CELNYTPETG DGDIEITRAL AINASFEVSL QFWSYLVERG GLPSPDEFIN TCPHESFVWG
     ESDIAFLRKR HQLLSAHHLF KDMEFSDDPR TLQDWMPLVM EHRDPMQKVA ATRVRYGSDV
     DFGSLTRNMV EHLQKNANFE LLLSHPVKSL KQTSDGRWNV QLSDSRNGGS KTIDAGFVFL
     GAGGGALPLL QKSGIAEGDG YGGFPVSGQW LVCKKPDIVK RHYAKVYGKA AIGAPPMSVP
     HLDTRIINGE PALLFGPYAG FTTKFLKTGS SFDLFGSIRA NNFGPIMSVG INNMDLTRYL
     IKEAMQSHSD RVKSLLNYFP EAKEDDWTLA EAGQRVQIIK RDAQGRGKLE FGTELVASKD
     GTLAALLGAS PGASVAVKAM VDVIERCFKD RLSSADWTAK LKEMIPSYGE SLVDNAELLH
     SVRSRTLSVL GLDKKRL