MQO_KLEPN
ID MQO_KLEPN Reviewed; 115 AA.
AC O32719;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Probable malate:quinone oxidoreductase;
DE EC=1.1.5.4;
DE AltName: Full=MQO;
DE AltName: Full=Malate dehydrogenase [quinone];
DE Flags: Fragment;
GN Name=mqo;
OS Klebsiella pneumoniae.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=573;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9208947; DOI=10.1111/j.1432-1033.1997.00530.x;
RA Hoenke S., Schmid M., Dimroth P.;
RT "Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate
RT decarboxylase and expression of the enzyme in Escherichia coli.";
RL Eur. J. Biochem. 246:530-538(1997).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000305}.
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DR EMBL; U95087; AAC45463.1; -; Genomic_DNA.
DR AlphaFoldDB; O32719; -.
DR UniPathway; UPA00223; UER01008.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT CHAIN <1..115
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_0000128719"
FT REGION 88..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
SQ SEQUENCE 115 AA; 12198 MW; 27D88C7E287CFF58 CRC64;
GTEVVVDQQK TISALLGASP GASTAAPITL NVLKQMFPQQ FNSPEWQSRI HAIVPSYGQK
LNGNVALTQQ VWDDTAATLQ LTKPPVIQMP AAAPTATAKP AETPREASPQ HDMAL