ID   MQO_KOCRD               Reviewed;         494 AA.
AC   B2GFJ0;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=KRH_10160;
OS   Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201).
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Kocuria.
OX   NCBI_TaxID=378753;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9341 / DSM 348 / NBRC 103217 / DC2201;
RX   PubMed=18408034; DOI=10.1128/jb.01853-07;
RA   Takarada H., Sekine M., Kosugi H., Matsuo Y., Fujisawa T., Omata S.,
RA   Kishi E., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.;
RT   "Complete genome sequence of the soil actinomycete Kocuria rhizophila.";
RL   J. Bacteriol. 190:4139-4146(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; AP009152; BAG29363.1; -; Genomic_DNA.
DR   AlphaFoldDB; B2GFJ0; -.
DR   SMR; B2GFJ0; -.
DR   STRING; 378753.KRH_10160; -.
DR   EnsemblBacteria; BAG29363; BAG29363; KRH_10160.
DR   KEGG; krh:KRH_10160; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_11; -.
DR   OMA; PHLDTRW; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000008838; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..494
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000099874"
SQ   SEQUENCE   494 AA;  53826 MW;  1C79909DA099316B CRC64;
     MTSPQPTETA DVVLVGAGIM SATLATLLND LQPEWRMLVL ERLDAAGLES SNAWNNAGTG
     HSALCELNYA PQAADGTVSA EKALTINEQF QVTRQMWSSL VENGTLEDPN TFINPVPHVS
     MVFGDDHADY LRARYDAFKP NKLFERMEFT EDRDLIAQWA PLTMHGRGAG RVAATFAPEG
     TDVDFGALTN QLLNHLQGRN ITVEYGQEVT TLDRQSDGSW LVSVVDRLNS DNNRVIRAGF
     VFLGAGGGAL PLLQKSKIKE AKGYGGFPVS GLFLRNTDPT VTAQHNAKVY GQASVGAPPM
     SVPHLDTRYV NGRRAIMFGP YGGFKPNFLK HGSLLDLPKS VRAHNLYPMT RAGMANLDLV
     KYLVGELTKT RSQRIDALHE YYPTAEESQW ELIEAGQRVQ VMKSDPQKGG VLQFGTELVT
     SADGSIGALL GASPGASTAV PIMLNLLSKC FPAKMSEWEP RIKELIPAYG RKLNDDPRLT
     DEIMGHTASV LGIK