ID   MQO_PAEAT               Reviewed;         501 AA.
AC   A1R7M9;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=AAur_2520;
OS   Paenarthrobacter aurescens (strain TC1).
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Paenarthrobacter.
OX   NCBI_TaxID=290340;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TC1;
RX   PubMed=17194220; DOI=10.1371/journal.pgen.0020214;
RA   Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B.,
RA   Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V.,
RA   Khouri H.M., Wackett L.P., Nelson K.E., Sadowsky M.J.;
RT   "Secrets of soil survival revealed by the genome sequence of Arthrobacter
RT   aurescens TC1.";
RL   PLoS Genet. 2:2094-2106(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABM07670.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000474; ABM07670.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; A1R7M9; -.
DR   STRING; 290340.AAur_2520; -.
DR   EnsemblBacteria; ABM07670; ABM07670; AAur_2520.
DR   KEGG; aau:AAur_2520; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_11; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000000637; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..501
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325485"
SQ   SEQUENCE   501 AA;  54163 MW;  06A4E726E3AC2804 CRC64;
     MTFISKTQHA DVVLIGGGIM SATLGAFIKQ LEPTWTISLF ERLDEAGLES SGPWNNAGTG
     HAALCELNYS PAAKDGSVDP SKALHINEQF QLSRQFWSHL VDSNVIGSPK GFINTVPHMS
     FVIGDDHSNF LKNRYEALKP NTLFRSMEYT EDQDQIAKWA PLIVKGRDRK QRVAATRAAE
     GTDVDFGALT RELTGYLQSS GAEVNYGHDV TNIHRAAGGG WDLSIKHPKS GEHGRIHAKF
     VFVGAGGGAL HLLQASGIPE SKGYGGFPVS GQFFRCTDDA ITSQHSAKVY GQASVGAPPM
     SVPHLDTRYV DGKRSLLFGP YAGFSTNFLK TSSYLDLPLS IRPGNIIPML AVAKDNMDLT
     AYLIKEVAKR HEAKVEALRE YYPEAAGGNW ELITAGQRVQ IIKKHPQKGG VLQFGTEVIA
     SRDGSIGALL GASPGASTAV PIMIELLQKS FPKNFKGWQS KLKDMMPGYG VKLNENPDLA
     AELEASTARS LQLEVANAIQ G