ID   MQO_PARMW               Reviewed;         502 AA.
AC   Q7U5L7;
DT   15-DEC-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=SYNW1686;
OS   Parasynechococcus marenigrum (strain WH8102).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Parasynechococcus; Parasynechococcus marenigrum.
OX   NCBI_TaxID=84588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH8102;
RX   PubMed=12917641; DOI=10.1038/nature01943;
RA   Palenik B., Brahamsha B., Larimer F.W., Land M.L., Hauser L., Chain P.,
RA   Lamerdin J.E., Regala W., Allen E.E., McCarren J., Paulsen I.T.,
RA   Dufresne A., Partensky F., Webb E.A., Waterbury J.;
RT   "The genome of a motile marine Synechococcus.";
RL   Nature 424:1037-1042(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; BX569693; CAE08201.1; -; Genomic_DNA.
DR   RefSeq; WP_011128548.1; NC_005070.1.
DR   AlphaFoldDB; Q7U5L7; -.
DR   STRING; 84588.SYNW1686; -.
DR   EnsemblBacteria; CAE08201; CAE08201; SYNW1686.
DR   KEGG; syw:SYNW1686; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_3; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001422; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..502
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000128757"
SQ   SEQUENCE   502 AA;  54428 MW;  2DCD6702206618B1 CRC64;
     MQQDGSFSAD ARFDAVLVGA GIMSATLAAL LHELDPGLRL LLVERLEGPA RESSAANNNA
     GTGHAANCEL NYTPMQADGT VATAKAVAIN AGFERSLEFW GSLRERGELD TSSFLHQAAH
     ISAVWTAENI AFLRQRFEQL SEIPAFAAMR WSEERTELTD WMPLVMAGRD LKQPVAATRI
     ERGTDVDFGA LTRAYLEPLQ RSGALCVEYG TQVRDIKRLR RGDMTEADWR VILQGPSGKR
     EVRAPFVFLG AGGGALPLLQ RSGIPEADDF AGFPVSGLWL VCGDAQLAAK QRAKVYGKAA
     VGAPPMSVPH LDTRWIDGQR SLLFGPFAGF SSKFLKQGSL FDLPSSVRPT NLLPMLQVGA
     TNIELVQYLI NQLRQSPEER HDALQQFMPT ARAEDWSLSV AGQRVQIIKR SKQGGRLQLG
     TEVVASMDGS LAALLGASPG ASTAVTIMLE VLQRCFKQRL ASAAWNERLQ ALLPSIGGDP
     VQDPALLLAM RQRSDALLDL QG