ID   MQO_PECAS               Reviewed;         527 AA.
AC   Q6D2L3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=ECA3082;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; BX950851; CAG75981.1; -; Genomic_DNA.
DR   RefSeq; WP_011094606.1; NC_004547.2.
DR   AlphaFoldDB; Q6D2L3; -.
DR   STRING; 218491.ECA3082; -.
DR   EnsemblBacteria; CAG75981; CAG75981; ECA3082.
DR   GeneID; 57209767; -.
DR   KEGG; eca:ECA3082; -.
DR   PATRIC; fig|218491.5.peg.3115; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..527
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000023800"
SQ   SEQUENCE   527 AA;  58123 MW;  35D674A15C000ACD CRC64;
     MKKLLAMFFC LSVVVSAPLA MAEDAKTTEK TTDVVLIGGG IMSSTLGVYL QELQPDWSID
     MVERMDNVAE ESSNGWNNAG TGHSAFMELN YTPDNPDGPI NISKALEITE AFEISRQFWS
     YQVKNGVLNN PHAFINSVPH ISFVWGDENT AFLKHRYDAM QHSTLYRGME FSDDPNTIKE
     WVPLVMEGRD PAQKIAATRM PIGTDVNYGE ITRQLVSAMK TKSNFALHLN SEVRDIKRNA
     DNTWSVTYAD LKNGEKESVI KAKFVFIGAG GAALKLLQKS GIPEADLYGG FPVGGEFLVT
     ENPEIVKRHM AKVYGKASVG APPMSVPHLD TRIFDGKPVL LFGPFATFSS KFLKNGSLWD
     LIGSVTFSNV MPMTHVGLDN FDLVKYLVSQ VMMDDDDRFA SLQEYFPNAK KEDWRLTVAG
     QRVQVIKKDD DKGGVLKLGT EIVSSQDGSI AALLGASPGA STAAPIMLSL LEKVFKDKVA
     TPEWQSKLKE IVPSYGQKLD GNIEMTNKIR SYTSSTLGLD YIEVKPE