ID   MQO_PECCP               Reviewed;         527 AA.
AC   C6DAM1;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=PC1_2825;
OS   Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=561230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP001657; ACT13855.1; -; Genomic_DNA.
DR   RefSeq; WP_015841015.1; NC_012917.1.
DR   AlphaFoldDB; C6DAM1; -.
DR   STRING; 561230.PC1_2825; -.
DR   EnsemblBacteria; ACT13855; ACT13855; PC1_2825.
DR   KEGG; pct:PC1_2825; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000002736; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..527
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000204202"
SQ   SEQUENCE   527 AA;  58178 MW;  A323FC4E3E75B4B3 CRC64;
     MKKLLAMFFC LTVVVNAPLA MAEDAKTTEK TTDVVLIGGG IMSSTLGVYL QELQPDWSID
     MVERMDNVAE ESSNGWNNAG TGHSAFMELN YTPDNPDGPI NISKALEITE AFEVSRQFWS
     YQVKNGVLNN PHSFINSVPH ISFVWGDENT AFLKHRYDAM QHSTLYRGME FSDDPNTIKE
     WAPLVMEGRD PAQKIAATRM PIGTDVNYGE ITRQLVDAMK TKSNFALHLN SEVRDIKRNA
     DNTWSVTYAD LKNGEKESVI KAKFVFIGAG GAALQLLQKT GIPEADLYGG FPVGGEFLVT
     ENPEIVKRHM AKVYGKASVG APPMSVPHLD TRIFDGKPVL LFGPFATFSS KFLKNGSLWD
     LIGSVTFSNV MPMTHVGLDN FDLVKYLIGQ VMMDDDDRFA SLKEYFPNAK KEDWRLTVAG
     QRVQIIKKDD DKGGVLKLGT EIVSSQDGSI AALLGASPGA STAAPIMLSL LEKVFKDKVA
     TPEWQSKLKE IVPSYGQKLD GNIEMTNKIR SYTSSTLGLD YIEVKPE