ID   MQO_PROMH               Reviewed;         498 AA.
AC   B4F088;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=PMI1931;
OS   Proteus mirabilis (strain HI4320).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Proteus.
OX   NCBI_TaxID=529507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI4320;
RX   PubMed=18375554; DOI=10.1128/jb.01981-07;
RA   Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S.,
RA   Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T.,
RA   Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA   Rabbinowitsch E., Walker D., Whithead S., Thomson N.R., Rather P.N.,
RA   Parkhill J., Mobley H.L.T.;
RT   "Complete genome sequence of uropathogenic Proteus mirabilis, a master of
RT   both adherence and motility.";
RL   J. Bacteriol. 190:4027-4037(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; AM942759; CAR43976.1; -; Genomic_DNA.
DR   RefSeq; WP_012368161.1; NC_010554.1.
DR   AlphaFoldDB; B4F088; -.
DR   STRING; 529507.PMI1931; -.
DR   EnsemblBacteria; CAR43976; CAR43976; PMI1931.
DR   GeneID; 6800210; -.
DR   KEGG; pmr:PMI1931; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000008319; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..498
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000099879"
SQ   SEQUENCE   498 AA;  55498 MW;  36339A033BAF4BEF CRC64;
     MNKTISEHVD VALIGAGIMS ATLGTLLKEL ESNLKVAMFE RLNDCGQESS NSWNNAGTGH
     AANCELNYTP PNPDGTVNIS KALEVNTEFD LSRQLWSYLV TKGKIADPRD FIHACPHMSF
     VWGADNVKFL HQRYRQMSAN HCYENMQYSE DKQQIEDWAP LIMEGRDPNQ QLAVTRVATG
     TDVDYGALTH LLVKQLSQQD NFELHYKHDV IDIKRNETGG WNIEVKDLTT HDKYLITAKY
     VFVGAGGRAI DLLQKSGIPE GKGYGGFPVS GIWLRCDEDK ISSRHHAKVY GKADVGSPPM
     SVPHLDTRII AGKRSLLFGP YAGFSSKFLK HGSYLDLFES IRPSNIEPML DVAKDNWSLT
     EYLIGQVLQT SAHQFEMLKQ FYPQAQHEDW QEAVAGQRVQ IIKPAAKHHG VLEFGTELIS
     SADKSFSVLL GASPGASTAA FIAINIIKSC FKQQLENEGW EDRLKTIIPT YGIDLKIDAD
     ACRNIRASTA KILKLETP