MQO_RALSO
ID MQO_RALSO Reviewed; 541 AA.
AC Q8XRL7;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=RSp0814;
GN ORFNames=RS01893;
OS Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OG Plasmid megaplasmid Rsp.
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Ralstonia.
OX NCBI_TaxID=267608;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GMI1000;
RX PubMed=11823852; DOI=10.1038/415497a;
RA Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL Nature 415:497-502(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC oxaloacetate from (S)-malate (quinone route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00212}.
CC -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC Rule:MF_00212}.
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DR EMBL; AL646053; CAD17965.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8XRL7; -.
DR STRING; 267608.RSp0814; -.
DR PRIDE; Q8XRL7; -.
DR EnsemblBacteria; CAD17965; CAD17965; RSp0814.
DR KEGG; rso:RSp0814; -.
DR eggNOG; COG0579; Bacteria.
DR HOGENOM; CLU_028151_0_0_4; -.
DR OMA; PHLDTRW; -.
DR UniPathway; UPA00223; UER01008.
DR Proteomes; UP000001436; Plasmid megaplasmid Rsp.
DR GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00212; MQO; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR006231; MQO.
DR Pfam; PF06039; Mqo; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE 3: Inferred from homology;
KW FAD; Flavoprotein; Oxidoreductase; Plasmid; Reference proteome;
KW Tricarboxylic acid cycle.
FT CHAIN 1..541
FT /note="Probable malate:quinone oxidoreductase"
FT /id="PRO_0000128736"
FT REGION 520..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 59441 MW; E060CB093B512B02 CRC64;
MVCLAAFSAQ AAETKKVDVL LVGGGIMSST LGVWLHELEP DWSMMMVERL DGVAQESSNG
WNNAGTGHSA LAELNYTPEK SNGKIDISKA VEINEGFQVT RQFWTYQVKT GVLKNPRSFI
NSTPHMSFVW GEDNVRYLKK RYEALQASPL FRGMQFSDDY DQISKWVPLM MEGRDRSQKV
AATWMPVGTD VNFGEITRQF VGYLQSQPQF TLSLSSEVRD IKRNDDGTWR VSYVNLKSGD
RQDVDTKFLF IGAGGGALRL LQASGIPEAR DFAAFPVGGS FLVTENPEVV NRHLAKAYGK
ASVGSPPMSV PHLDTRVIDG KRIILFGPFA TFSTKFLKNG SYMDLFGSTT SHNVMPMLHV
GVDEFPLVQY LAGQLMLSDE DRFNALKEYF PLAKKEDWRL WQAGQRVQII QRDEAKGGIL
KLGTQIVKSK DGTIAGLLGA SPGASTAAPI MLGVLETVFK DKLATPAWQQ KVRQMIPTYG
IKLNDNPAKV YEEWVATAEA LQLSPPPRID LRVTPAAPAA KPAAGAAQQA KPAKATADIA
L
